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Cellular Signalling|September 18, 2013
Reversible inhibitors of regulators of G-protein signaling identified in a high-throughput cell-based calcium signaling assayAndrew J Storaska, Jian P Mei, Meng Wu, et al.Bioorganic & Medicinal Chemistry Letters|May 29, 2016
Discovery and characterization of a novel series of N-phenylsulfonyl-1H-pyrrole picolinamides as positive allosteric modulators of the metabotropic glutamate receptor 4 (mGlu4)Rocco D Gogliotti, Anna L Blobaum, Ryan M Morrison, et al.Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie|January 25, 2023
Identification and characterization of a first-generation inhibitor of claudin-1 in colon cancer progression and metastasisIram Fatima, Jaya Prakash Uppada, Yashpal S Chhonker, et al.Bioorganic & Medicinal Chemistry Letters|December 4, 2012
Further exploration of M₁ allosteric agonists: subtle structural changes abolish M₁ allosteric agonism and result in pan-mAChR orthosteric antagonismDouglas J Sheffler, Christian Sevel, Uyen Le, et al.Journal of Medicinal Chemistry|January 21, 2011
Discovery, synthesis, and structure-activity relationship development of a series of N-(4-acetamido)phenylpicolinamides as positive allosteric modulators of metabotropic glutamate receptor 4 (mGlu(4)) with CNS exposure in ratsDarren W Engers, Julie R Field, Uyen Le, et al.Bioorganic & Medicinal Chemistry Letters|May 25, 2005
Design, synthesis, and biological activity of potent and selective inhibitors of mast cell tryptaseCorey R Hopkins, Mark Czekaj, Steven S Kaye, et al.The Journal of Pharmacology and Experimental Therapeutics|October 2, 2014
Specific activin receptor-like kinase 3 inhibitors enhance liver regenerationDaisuke Tsugawa, Yuki Oya, Ryota Masuzaki, et al.ACS Chemical Biology|August 20, 2014
Chemical modulation of mutant mGlu1 receptors derived from deleterious GRM1 mutations found in schizophrenicsHyekyung P Cho, Pedro M Garcia-Barrantes, John T Brogan, et al.ACS Chemical Neuroscience|July 22, 2016
Development and Antiparkinsonian Activity of VU0418506, a Selective Positive Allosteric Modulator of Metabotropic Glutamate Receptor 4 Homomers without Activity at mGlu2/4 HeteromersColleen M Niswender, Carrie K Jones, Xin Lin, et al.Journal of Medicinal Chemistry|September 25, 2018
Discovery, Structure-Activity Relationship, and Biological Characterization of a Novel Series of 6-((1 H-Pyrazolo[4,3- b]pyridin-3-yl)amino)-benzo[ d]isothiazole-3-carboxamides as Positive Allosteric Modulators of the Metabotropic Glutamate Receptor 4 (mGlu<sub>4</sub>)Sean R Bollinger, Darren W Engers, Joseph D Panarese, et al.Pageof 13