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ACS Chemical Neuroscience|August 24, 2018
Discovery and Characterization of VU0529331, a Synthetic Small-Molecule Activator of Homomeric G Protein-Gated, Inwardly Rectifying, Potassium (GIRK) ChannelsKrystian A Kozek, Yu Du, Swagat Sharma, et al.
Chemmedchem|April 16, 2025
Further Structure-Activity Relationship of G Protein-Gated Inwardly Rectifying Potassium Channels 1/2 Activators: Synthesis and Biological Characterization of In Vitro Tool CompoundsSumaiya Nahid, Fahad Imtiaz Rahman, Yu Du, et al.
ACS Chemical Neuroscience|November 30, 2011
Discovery, Synthesis, and Structure Activity Relationship of a Series of N-Aryl- bicyclo[2.2.1]heptane-2-carboxamides: Characterization of ML213 as a Novel KCNQ2 and KCNQ4 Potassium Channel OpenerHaibo Yu, Meng Wu, Steven D Townsend, et al.
Journal of Medicinal Chemistry|May 28, 2009
Synthesis and evaluation of a series of heterobiarylamides that are centrally penetrant metabotropic glutamate receptor 4 (mGluR4) positive allosteric modulators (PAMs)Darren W Engers, Colleen M Niswender, C David Weaver, et al.
Neuro-Oncology|December 20, 2015
Bone morphogenetic protein signaling promotes tumorigenesis in a murine model of high-grade gliomaLaura D Hover, Philip Owens, Alexander L Munden, et al.
ACS Chemical Biology|December 22, 2009
In vivo structure-activity relationship study of dorsomorphin analogues identifies selective VEGF and BMP inhibitorsJijun Hao, Joshua N Ho, Jana A Lewis, et al.
ACS Medicinal Chemistry Letters|September 16, 2014
Discovery and Characterization of ML398, a Potent and Selective Antagonist of the D4 Receptor with in Vivo ActivityCynthia B Berry, Michael Bubser, Carrie K Jones, et al.
Neuropharmacology|March 10, 2015
Pharmacological stimulation of metabotropic glutamate receptor type 4 in a rat model of Parkinson's disease and L-DOPA-induced dyskinesia: Comparison between a positive allosteric modulator and an orthosteric agonistHanna Iderberg, Natallia Maslava, Analisa D Thompson, et al.
Bioorganic & Medicinal Chemistry Letters|August 5, 2020
Discovery, synthesis and characterization of a series of 7-aryl-imidazo[1,2-a]pyridine-3-ylquinolines as activin-like kinase (ALK) inhibitorsDarren W Engers, Sean R Bollinger, Andrew S Felts, et al.
Frontiers in Medicine|October 8, 2021
TRPC5 Channel Inhibition Protects Podocytes in Puromycin-Aminonucleoside Induced Nephrosis ModelsYiming Zhou, Choah Kim, Juan Lorenzo B Pablo, et al.
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