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ACS Medicinal Chemistry Letters|January 21, 2022
Discovery of Spiro-azaindoline Inhibitors of Hematopoietic Progenitor Kinase 1 (HPK1)Bryan K Chan, Eileen Seward, Michael Lainchbury, et al.Journal of Medicinal Chemistry|October 24, 2022
Overcoming Preclinical Safety Obstacles to Discover (<i>S</i>)-<i>N</i>-((1,2,3,5,6,7-Hexahydro-<i>s</i>-indacen-4-yl)carbamoyl)-6-(methylamino)-6,7-dihydro-5<i>H</i>-pyrazolo[5,1-<i>b</i>][1,3]oxazine-3-sulfonamide (GDC-2394): A Potent and Selective NLRP3 InhibitorChristopher McBride, Lynnie Trzoss, Davide Povero, et al.Pageof 4