Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Filters

Cynthia S Dowd

Showing results (21-30 of 47) with videos related to

Pageof 5
Sort By:
Bioorganic & Medicinal Chemistry Letters|August 23, 2017
Design, synthesis, and evaluation of substituted nicotinamide adenine dinucleotide (NAD<sup>+</sup>) synthetase inhibitors as potential antitubercular agentsXu Wang, Yong-Mo Ahn, Adam G Lentscher, et al.
Plos One|October 19, 2012
Lipophilic prodrugs of FR900098 are antimicrobial against Francisella novicida in vivo and in vitro and show GlpT independent efficacyElizabeth S McKenney, Michelle Sargent, Hameed Khan, et al.
Journal of Medicinal Chemistry|February 13, 2009
Structure-activity relationships of antitubercular nitroimidazoles. 1. Structural features associated with aerobic and anaerobic activities of 4- and 5-nitroimidazolesPilho Kim, Liang Zhang, Ujjini H Manjunatha, et al.
Proceedings of the National Academy of Sciences of the United States of America|January 3, 2006
Identification of a nitroimidazo-oxazine-specific protein involved in PA-824 resistance in Mycobacterium tuberculosisUjjini H Manjunatha, Helena Boshoff, Cynthia S Dowd, et al.
Bioorganic & Medicinal Chemistry Letters|December 24, 2013
The effect of chain length and unsaturation on Mtb Dxr inhibition and antitubercular killing activity of FR900098 analogsEmily R Jackson, Géraldine San Jose, Robert C Brothers, et al.
Chemmedchem|August 4, 2016
Targeting an Aromatic Hotspot in Plasmodium falciparum 1-Deoxy-d-xylulose-5-phosphate Reductoisomerase with β-Arylpropyl Analogues of FosmidomycinSanjeewani Sooriyaarachchi, René Chofor, Martijn D P Risseeuw, et al.
Medchemcomm|August 6, 2013
Design of Potential Bisubstrate Inhibitors against <i>Mycobacterium tuberculosis</i> (Mtb) 1-Deoxy-D-Xylulose 5-Phosphate Reductoisomerase (Dxr)-Evidence of a Novel Binding ModeGéraldine San Jose, Emily R Jackson, Eugene Uh, et al.
RSC Medicinal Chemistry|July 19, 2024
Inhibition of DXR in the MEP pathway with lipophilic <i>N</i>-alkoxyaryl FR900098 analogsDarean Bague, Ruiqin Wang, Dana Hodge, et al.
Plos One|August 30, 2014
Kinetic characterization and allosteric inhibition of the Yersinia pestis 1-deoxy-D-xylulose 5-phosphate reductoisomerase (MEP synthase)Amanda Haymond, Chinchu Johny, Tyrone Dowdy, et al.
Analytical Biochemistry|November 29, 2017
A high-throughput screening campaign to identify inhibitors of DXP reductoisomerase (IspC) and MEP cytidylyltransferase (IspD)Amanda Haymond, Tyrone Dowdy, Chinchu Johny, et al.
Pageof 5

Showing results (21-30 of 47) with videos related to

Sort By:
Pageof 5
Bioorganic & Medicinal Chemistry Letters|August 23, 2017
Design, synthesis, and evaluation of substituted nicotinamide adenine dinucleotide (NAD<sup>+</sup>) synthetase inhibitors as potential antitubercular agentsXu Wang, Yong-Mo Ahn, Adam G Lentscher, et al.
Plos One|October 19, 2012
Lipophilic prodrugs of FR900098 are antimicrobial against Francisella novicida in vivo and in vitro and show GlpT independent efficacyElizabeth S McKenney, Michelle Sargent, Hameed Khan, et al.
Journal of Medicinal Chemistry|February 13, 2009
Structure-activity relationships of antitubercular nitroimidazoles. 1. Structural features associated with aerobic and anaerobic activities of 4- and 5-nitroimidazolesPilho Kim, Liang Zhang, Ujjini H Manjunatha, et al.
Proceedings of the National Academy of Sciences of the United States of America|January 3, 2006
Identification of a nitroimidazo-oxazine-specific protein involved in PA-824 resistance in Mycobacterium tuberculosisUjjini H Manjunatha, Helena Boshoff, Cynthia S Dowd, et al.
Bioorganic & Medicinal Chemistry Letters|December 24, 2013
The effect of chain length and unsaturation on Mtb Dxr inhibition and antitubercular killing activity of FR900098 analogsEmily R Jackson, Géraldine San Jose, Robert C Brothers, et al.
Chemmedchem|August 4, 2016
Targeting an Aromatic Hotspot in Plasmodium falciparum 1-Deoxy-d-xylulose-5-phosphate Reductoisomerase with β-Arylpropyl Analogues of FosmidomycinSanjeewani Sooriyaarachchi, René Chofor, Martijn D P Risseeuw, et al.
Medchemcomm|August 6, 2013
Design of Potential Bisubstrate Inhibitors against <i>Mycobacterium tuberculosis</i> (Mtb) 1-Deoxy-D-Xylulose 5-Phosphate Reductoisomerase (Dxr)-Evidence of a Novel Binding ModeGéraldine San Jose, Emily R Jackson, Eugene Uh, et al.
RSC Medicinal Chemistry|July 19, 2024
Inhibition of DXR in the MEP pathway with lipophilic <i>N</i>-alkoxyaryl FR900098 analogsDarean Bague, Ruiqin Wang, Dana Hodge, et al.
Plos One|August 30, 2014
Kinetic characterization and allosteric inhibition of the Yersinia pestis 1-deoxy-D-xylulose 5-phosphate reductoisomerase (MEP synthase)Amanda Haymond, Chinchu Johny, Tyrone Dowdy, et al.
Analytical Biochemistry|November 29, 2017
A high-throughput screening campaign to identify inhibitors of DXP reductoisomerase (IspC) and MEP cytidylyltransferase (IspD)Amanda Haymond, Tyrone Dowdy, Chinchu Johny, et al.
Pageof 5