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Cell Reports|July 29, 2022
High-risk neuroblastoma with NF1 loss of function is targetable using SHP2 inhibitionJinyang Cai, Sheeba Jacob, Richard Kurupi, et al.Molecular Cancer Therapeutics|June 5, 2021
Venetoclax-based Rational Combinations are Effective in Models of <i>MYCN</i>-amplified NeuroblastomaKrista M Dalton, Kateryna Krytska, Timothy L Lochmann, et al.Nature Communications|May 18, 2019
Functional linkage of gene fusions to cancer cell fitness assessed by pharmacological and CRISPR-Cas9 screeningGabriele Picco, Elisabeth D Chen, Luz Garcia Alonso, et al.Proceedings of the National Academy of Sciences of the United States of America|March 25, 2021
Catastrophic ATP loss underlies a metabolic combination therapy tailored for <i>MYCN</i>-amplified neuroblastomaKrista M Dalton, Timothy L Lochmann, Konstantinos V Floros, et al.Plos One|August 3, 2017
Cancer stem cell-related gene expression as a potential biomarker of response for first-in-class imipridone ONC201 in solid tumorsVarun V Prabhu, Amriti R Lulla, Neel S Madhukar, et al.Clinical Cancer Research : an Official Journal of the American Association for Cancer Research|October 24, 2018
The Ewing Family of Tumors Relies on BCL-2 and BCL-X<sub>L</sub> to Escape PARP Inhibitor ToxicityDaniel A R Heisey, Timothy L Lochmann, Konstantinos V Floros, et al.Clinical Cancer Research : an Official Journal of the American Association for Cancer Research|May 31, 2018
Target-Based Screening against eIF4A1 Reveals the Marine Natural Product Elatol as a Novel Inhibitor of Translation Initiation with <i>In Vivo</i> Antitumor ActivityTara L Peters, Joseph Tillotson, Alison M Yeomans, et al.PNAS Nexus|January 30, 2023
Genomic screening reveals ubiquitin-like modifier activating enzyme 1 as a potent and druggable target in c-MYC-high triple negative breast cancer modelsSheeba Jacob, Tia H Turner, Jinyang Cai, et al.Nature Cancer|April 18, 2024
PERCEPTION predicts patient response and resistance to treatment using single-cell transcriptomics of their tumorsSanju Sinha, Rahulsimham Vegesna, Sumit Mukherjee, et al.Clinical Cancer Research : an Official Journal of the American Association for Cancer Research|November 10, 2017
Venetoclax Is Effective in Small-Cell Lung Cancers with High BCL-2 ExpressionTimothy L Lochmann, Konstantinos V Floros, Mitra Naseri, et al.Pageof 11