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Movement Disorders : Official Journal of the Movement Disorder Society|June 15, 2016
Ser(P)-1292 LRRK2 in urinary exosomes is elevated in idiopathic Parkinson's diseaseKyle B Fraser, Ashlee B Rawlins, Rachel G Clark, et al.Journal of Pharmaceutical Sciences|May 26, 2018
Biopharmaceutical Characterization and Oral Efficacy of a New Rapid Acting Antidepressant Ro 25-6981Venkata K Yellepeddi, Maryia Y Zhudeva, Fereshteh Movahedi, et al.Acta Crystallographica. Section D, Structural Biology|November 7, 2019
Antibody fragments structurally enable a drug-discovery campaign on the cancer target Mcl-1Jakub Luptak, Michal Bista, David Fisher, et al.Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences|October 6, 2014
Reaction profiling by ultra high-pressure liquid chromatography/time-of-flight mass spectrometry in support of the synthesis of DNA-encoded librariesLeonard O Hargiss, G Greg Zipp, Theodore C Jessop, et al.SLAS Discovery : Advancing Life Sciences R & D|December 8, 2020
Regenerable Biosensors for Small-Molecule Kinetic Characterization Using SPRAnders Gunnarsson, Christopher J Stubbs, Philip B Rawlins, et al.ACS Medicinal Chemistry Letters|January 16, 2015
Discovery of a Type III Inhibitor of LIM Kinase 2 That Binds in a DFG-Out ConformationNicole C Goodwin, Giovanni Cianchetta, Hugh A Burgoon, et al.The Biochemical Journal|October 29, 2020
A-loop interactions in Mer tyrosine kinase give rise to inhibitors with two-step mechanism and long residence time of bindingAlexander Pflug, Marianne Schimpl, J Willem M Nissink, et al.ACS Medicinal Chemistry Letters|July 21, 2022
Surface Plasmon Resonance Screening to Identify Active and Selective Adenosine Receptor Binding FragmentsClaire Shepherd, Sean Robinson, Alice Berizzi, et al.Nature Chemical Biology|September 6, 2016
Inhibition of Mcl-1 through covalent modification of a noncatalytic lysine side chainGizem Akçay, Matthew A Belmonte, Brian Aquila, et al.Proceedings of the National Academy of Sciences of the United States of America|May 15, 2023
Design of rigid protein-protein interaction inhibitors enables targeting of undruggable Mcl-1David Hargreaves, Rodrigo J Carbajo, Michael S Bodnarchuk, et al.Pageof 15