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Chemmedchem
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April 3, 2020
Computationally Empowered Workflow Identifies Novel Covalent Allosteric Binders for KRAS<sup>G12C</sup>
Jérémie Mortier, Anders Friberg, Volker Badock, et al.
Bioorganic & Medicinal Chemistry Letters
|
December 7, 2007
Alpha,beta-cyclic-beta-benzamido hydroxamic acids: novel templates for the design, synthesis, and evaluation of selective inhibitors of TNF-alpha converting enzyme (TACE)
Gregory R Ott, Naoyuki Asakawa, Zhonghui Lu, et al.
Bioorganic & Medicinal Chemistry Letters
|
February 1, 2008
Alpha,Beta-cyclic-beta-benzamido hydroxamic acids: Novel oxaspiro[4.4]nonane templates for the discovery of potent, selective, orally bioavailable inhibitors of tumor necrosis factor-alpha converting enzyme (TACE)
Gregory R Ott, Naoyuki Asakawa, Rui-Qin Liu, et al.
Bioorganic & Medicinal Chemistry
|
September 1, 2000
The discovery of 4-(3-pentylamino)-2,7-dimethyl-8-(2-methyl-4-methoxyphenyl)-pyrazolo-[1 ,5-a]-pyrimidine: a corticotropin-releasing factor (hCRF1) antagonist
P J Gilligan, C Baldauf, A Cocuzza, et al.
Journal of Medicinal Chemistry
|
May 28, 2004
Sultam hydroxamates as novel matrix metalloproteinase inhibitors
Robert J Cherney, Ruowei Mo, Dayton T Meyer, et al.
Journal of Computer-Aided Molecular Design
|
December 26, 2016
Collaborating to improve the use of free-energy and other quantitative methods in drug discovery
Bradley Sherborne, Veerabahu Shanmugasundaram, Alan C Cheng, et al.
Bioorganic & Medicinal Chemistry Letters
|
November 23, 2007
Discovery of beta-benzamido hydroxamic acids as potent, selective, and orally bioavailable TACE inhibitors
James J-W Duan, Lihua Chen, Zhonghui Lu, et al.
Journal of Medicinal Chemistry
|
November 1, 2002
Discovery of gamma-lactam hydroxamic acids as selective inhibitors of tumor necrosis factor alpha converting enzyme: design, synthesis, and structure-activity relationships
James J-W Duan, Lihua Chen, Zelda R Wasserman, et al.
The Journal of Physical Chemistry. B
|
March 7, 2025
Prospective Evaluation of Structure-Based Simulations Reveal Their Ability to Predict the Impact of Kinase Mutations on Inhibitor Binding
Sukrit Singh, Vytautas Gapsys, Matteo Aldeghi, et al.
Toxicology and Applied Pharmacology
|
November 15, 2000
The species-dependent metabolism of efavirenz produces a nephrotoxic glutathione conjugate in rats
A E Mutlib, R J Gerson, P C Meunier, et al.
Page
of 12
Search research articles
Search
Showing results (91-100 of 120) with videos related to
Sort By:
Page
of 12
Chemmedchem
|
April 3, 2020
Computationally Empowered Workflow Identifies Novel Covalent Allosteric Binders for KRAS<sup>G12C</sup>
Jérémie Mortier, Anders Friberg, Volker Badock, et al.
Bioorganic & Medicinal Chemistry Letters
|
December 7, 2007
Alpha,beta-cyclic-beta-benzamido hydroxamic acids: novel templates for the design, synthesis, and evaluation of selective inhibitors of TNF-alpha converting enzyme (TACE)
Gregory R Ott, Naoyuki Asakawa, Zhonghui Lu, et al.
Bioorganic & Medicinal Chemistry Letters
|
February 1, 2008
Alpha,Beta-cyclic-beta-benzamido hydroxamic acids: Novel oxaspiro[4.4]nonane templates for the discovery of potent, selective, orally bioavailable inhibitors of tumor necrosis factor-alpha converting enzyme (TACE)
Gregory R Ott, Naoyuki Asakawa, Rui-Qin Liu, et al.
Bioorganic & Medicinal Chemistry
|
September 1, 2000
The discovery of 4-(3-pentylamino)-2,7-dimethyl-8-(2-methyl-4-methoxyphenyl)-pyrazolo-[1 ,5-a]-pyrimidine: a corticotropin-releasing factor (hCRF1) antagonist
P J Gilligan, C Baldauf, A Cocuzza, et al.
Journal of Medicinal Chemistry
|
May 28, 2004
Sultam hydroxamates as novel matrix metalloproteinase inhibitors
Robert J Cherney, Ruowei Mo, Dayton T Meyer, et al.
Journal of Computer-Aided Molecular Design
|
December 26, 2016
Collaborating to improve the use of free-energy and other quantitative methods in drug discovery
Bradley Sherborne, Veerabahu Shanmugasundaram, Alan C Cheng, et al.
Bioorganic & Medicinal Chemistry Letters
|
November 23, 2007
Discovery of beta-benzamido hydroxamic acids as potent, selective, and orally bioavailable TACE inhibitors
James J-W Duan, Lihua Chen, Zhonghui Lu, et al.
Journal of Medicinal Chemistry
|
November 1, 2002
Discovery of gamma-lactam hydroxamic acids as selective inhibitors of tumor necrosis factor alpha converting enzyme: design, synthesis, and structure-activity relationships
James J-W Duan, Lihua Chen, Zelda R Wasserman, et al.
The Journal of Physical Chemistry. B
|
March 7, 2025
Prospective Evaluation of Structure-Based Simulations Reveal Their Ability to Predict the Impact of Kinase Mutations on Inhibitor Binding
Sukrit Singh, Vytautas Gapsys, Matteo Aldeghi, et al.
Toxicology and Applied Pharmacology
|
November 15, 2000
The species-dependent metabolism of efavirenz produces a nephrotoxic glutathione conjugate in rats
A E Mutlib, R J Gerson, P C Meunier, et al.
Page
of 12