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Bioorganic & Medicinal Chemistry|September 17, 2011
Lead identification of β-lactam and related imine inhibitors of the molecular chaperone heat shock protein 90Niamh M O'Boyle, Andrew J S Knox, Trevor T Price, et al.
Pharmaceuticals (Basel, Switzerland)|January 23, 2020
Design, Synthesis and Biochemical Evaluation of Novel Ethanoanthracenes and Related Compounds to Target Burkitt's LymphomaAndrew J Byrne, Sandra A Bright, James P McKeown, et al.
RSC Chemical Biology|April 5, 2024
Tracking the cellular uptake and phototoxicity of Ru(ii)-polypyridyl-1,8-naphthalimide Tröger's base conjugatesSandra A Bright, MariaLuisa Erby, Fergus E Poynton, et al.
Journal of Medicinal Chemistry|January 28, 2012
"True" antiandrogens-selective non-ligand-binding pocket disruptors of androgen receptor-coactivator interactions: novel tools for prostate cancerLaura Caboni, Gemma K Kinsella, Fernando Blanco, et al.
The Journal of Pharmacology and Experimental Therapeutics|January 10, 2009
The microtubule-targeting agents, PBOX-6 [pyrrolobenzoxazepine 7-[(dimethylcarbamoyl)oxy]-6-(2-naphthyl)pyrrolo-[2,1-d] (1,5)-benzoxazepine] and paclitaxel, induce nucleocytoplasmic redistribution of the peptidyl-prolyl isomerases, cyclophilin A and pin1, in malignant hematopoietic cellsFiona T Bane, John H Bannon, Stephen R Pennington, et al.
Investigational New Drugs|February 18, 2016
The novel pyrrolo-1,5-benzoxazepine, PBOX-15, synergistically enhances the apoptotic efficacy of imatinib in gastrointestinal stromal tumours; suggested mechanism of action of PBOX-15Paula Kinsella, Lisa M Greene, Sandra A Bright, et al.
Journal of Medicinal Chemistry|April 1, 2009
Integration of ligand and structure-based virtual screening for the identification of the first dual targeting agent for heat shock protein 90 (Hsp90) and tubulinAndrew J S Knox, Trevor Price, Michal Pawlak, et al.
Chemistry (Weinheim an Der Bergstrasse, Germany)|November 25, 2021
Real-Time Multi-Photon Tracking and Bioimaging of Glycosylated Theranostic Prodrugs upon Specific Enzyme Triggered ReleaseElena Calatrava-Pérez, Luke A Marchetti, Gavin J McManus, et al.
Chemical Communications (Cambridge, England)|October 11, 2016
Glycosidase activated release of fluorescent 1,8-naphthalimide probes for tumor cell imaging from glycosylated 'pro-probes'Elena Calatrava-Pérez, Sandra A Bright, Stefan Achermann, et al.
Bioorganic & Medicinal Chemistry|January 14, 2011
Synthesis and serotonin transporter activity of 1,3-bis(aryl)-2-nitro-1-propenes as a new class of anticancer agentsYvonne M McNamara, Suzanne M Cloonan, Andrew J S Knox, et al.
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