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JBMR Plus|June 7, 2023
A Mouse Model with a Frameshift Mutation in the Nuclear Factor I/X (NFIX) Gene Has Phenotypic Features of Marshall-Smith SyndromeKreepa G Kooblall, Mark Stevenson, Michelle Stewart, et al.Science (New York, N.Y.)|June 6, 2024
Determining the ERK-regulated phosphoproteome driving KRAS-mutant cancerJennifer E Klomp, J Nathaniel Diehl, Jeffrey A Klomp, et al.Cancer Research|November 5, 2021
Aberrant Expression and Subcellular Localization of ECT2 Drives Colorectal Cancer Progression and GrowthDanielle R Cook, Melissa Kang, Timothy D Martin, et al.Science Signaling|September 30, 2025
Defining the MYC-regulated transcriptome and kinome that support KRAS- and ERK-dependent growth of pancreatic cancerPriya S Hibshman, Clint A Stalnecker, Jeffrey A Klomp, et al.Journal of Medicinal Chemistry|June 27, 2008
Kinesin spindle protein (KSP) inhibitors. 9. Discovery of (2S)-4-(2,5-difluorophenyl)-n-[(3R,4S)-3-fluoro-1-methylpiperidin-4-yl]-2-(hydroxymethyl)-N-methyl-2-phenyl-2,5-dihydro-1H-pyrrole-1-carboxamide (MK-0731) for the treatment of taxane-refractory cancerChristopher D Cox, Paul J Coleman, Michael J Breslin, et al.Cell Reports|December 1, 2021
CHK1 protects oncogenic KRAS-expressing cells from DNA damage and is a target for pancreatic cancer treatmentJennifer E Klomp, Ye S Lee, Craig M Goodwin, et al.Chemmedchem|February 7, 2012
Discovery of [(2R,5R)-5-{[(5-fluoropyridin-2-yl)oxy]methyl}-2-methylpiperidin-1-yl][5-methyl-2-(pyrimidin-2-yl)phenyl]methanone (MK-6096): a dual orexin receptor antagonist with potent sleep-promoting propertiesPaul J Coleman, John D Schreier, Christopher D Cox, et al.Bioorganic & Medicinal Chemistry Letters|September 25, 2014
Discovery of MK-3697: a selective orexin 2 receptor antagonist (2-SORA) for the treatment of insomniaAnthony J Roecker, Thomas S Reger, M Christa Mattern, et al.Cancer Discovery|October 26, 2019
Atypical KRASG12R Mutant Is Impaired in PI3K Signaling and Macropinocytosis in Pancreatic CancerG Aaron Hobbs, Nicole M Baker, Anne M Miermont, et al.Nature Communications|June 30, 2022
An essential role for tungsten in the ecology and evolution of a previously uncultivated lineage of anaerobic, thermophilic ArchaeaSteffen Buessecker, Marike Palmer, Dengxun Lai, et al.Pageof 172