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Showing results (41-50 of 70) with videos related to

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Bioorganic & Medicinal Chemistry Letters|November 6, 2007
Design and synthesis of potent amido- and benzyl-substituted cis-3-amino-4-(2-cyanopyrrolidide)pyrrolidinyl DPP-IV inhibitorsJ W Corbett, K Dirico, W Song, et al.
Journal of Medicinal Chemistry|April 24, 2014
Structural basis for isoform selectivity in a class of benzothiazole inhibitors of phosphoinositide 3-kinase γPhilip N Collier, Gabriel Martinez-Botella, Mark Cornebise, et al.
Biochemistry|January 27, 2010
Refolding and characterization of a soluble ectodomain complex of the calcitonin gene-related peptide receptorChristopher M Koth, Norzehan Abdul-Manan, Christopher A Lepre, et al.
Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine|December 12, 2018
Quantitative Analysis of <sup>18</sup>F-PF-06684511, a Novel PET Radioligand for Selective β-Secretase 1 Imaging, in Nonhuman Primate BrainAkihiro Takano, Laigao Chen, Sangram Nag, et al.
The Journal of Pharmacology and Experimental Therapeutics|March 4, 2005
Use of a physiologically based pharmacokinetic model to study the time to reach brain equilibrium: an experimental analysis of the role of blood-brain barrier permeability, plasma protein binding, and brain tissue bindingXingrong Liu, Bill J Smith, Cuiping Chen, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|June 9, 2006
Evaluation of cerebrospinal fluid concentration and plasma free concentration as a surrogate measurement for brain free concentrationXingrong Liu, Bill J Smith, Cuiping Chen, et al.
Bioorganic & Medicinal Chemistry Letters|April 5, 2011
1,5-Substituted nipecotic amides: selective PDE8 inhibitors displaying diastereomer-dependent microsomal stabilityMichael P DeNinno, Stephen W Wright, Michael S Visser, et al.
Bioorganic & Medicinal Chemistry Letters|February 18, 2011
1-((3S,4S)-4-amino-1-(4-substituted-1,3,5-triazin-2-yl) pyrrolidin-3-yl)-5,5-difluoropiperidin-2-one inhibitors of DPP-4 for the treatment of type 2 diabetesKim M Andrews, David A Beebe, John W Benbow, et al.
Bioorganic & Medicinal Chemistry Letters|April 7, 2009
Synthesis and SAR of 1,2,3,4-tetrahydroisoquinolin-1-ones as novel G-protein-coupled receptor 40 (GPR40) antagonistsPaul S Humphries, John W Benbow, Paul D Bonin, et al.
Bioorganic & Medicinal Chemistry Letters|August 4, 2012
Discovery of triazolopyrimidine-based PDE8B inhibitors: exceptionally ligand-efficient and lipophilic ligand-efficient compounds for the treatment of diabetesMichael P DeNinno, Stephen W Wright, John B Etienne, et al.
Pageof 7

Showing results (41-50 of 70) with videos related to

Sort By:
Pageof 7
Bioorganic & Medicinal Chemistry Letters|November 6, 2007
Design and synthesis of potent amido- and benzyl-substituted cis-3-amino-4-(2-cyanopyrrolidide)pyrrolidinyl DPP-IV inhibitorsJ W Corbett, K Dirico, W Song, et al.
Journal of Medicinal Chemistry|April 24, 2014
Structural basis for isoform selectivity in a class of benzothiazole inhibitors of phosphoinositide 3-kinase γPhilip N Collier, Gabriel Martinez-Botella, Mark Cornebise, et al.
Biochemistry|January 27, 2010
Refolding and characterization of a soluble ectodomain complex of the calcitonin gene-related peptide receptorChristopher M Koth, Norzehan Abdul-Manan, Christopher A Lepre, et al.
Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine|December 12, 2018
Quantitative Analysis of <sup>18</sup>F-PF-06684511, a Novel PET Radioligand for Selective β-Secretase 1 Imaging, in Nonhuman Primate BrainAkihiro Takano, Laigao Chen, Sangram Nag, et al.
The Journal of Pharmacology and Experimental Therapeutics|March 4, 2005
Use of a physiologically based pharmacokinetic model to study the time to reach brain equilibrium: an experimental analysis of the role of blood-brain barrier permeability, plasma protein binding, and brain tissue bindingXingrong Liu, Bill J Smith, Cuiping Chen, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|June 9, 2006
Evaluation of cerebrospinal fluid concentration and plasma free concentration as a surrogate measurement for brain free concentrationXingrong Liu, Bill J Smith, Cuiping Chen, et al.
Bioorganic & Medicinal Chemistry Letters|April 5, 2011
1,5-Substituted nipecotic amides: selective PDE8 inhibitors displaying diastereomer-dependent microsomal stabilityMichael P DeNinno, Stephen W Wright, Michael S Visser, et al.
Bioorganic & Medicinal Chemistry Letters|February 18, 2011
1-((3S,4S)-4-amino-1-(4-substituted-1,3,5-triazin-2-yl) pyrrolidin-3-yl)-5,5-difluoropiperidin-2-one inhibitors of DPP-4 for the treatment of type 2 diabetesKim M Andrews, David A Beebe, John W Benbow, et al.
Bioorganic & Medicinal Chemistry Letters|April 7, 2009
Synthesis and SAR of 1,2,3,4-tetrahydroisoquinolin-1-ones as novel G-protein-coupled receptor 40 (GPR40) antagonistsPaul S Humphries, John W Benbow, Paul D Bonin, et al.
Bioorganic & Medicinal Chemistry Letters|August 4, 2012
Discovery of triazolopyrimidine-based PDE8B inhibitors: exceptionally ligand-efficient and lipophilic ligand-efficient compounds for the treatment of diabetesMichael P DeNinno, Stephen W Wright, John B Etienne, et al.
Pageof 7