Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Filters

D Doran

Showing results (51-60 of 70) with videos related to

Pageof 7
Sort By:
Journal of Medicinal Chemistry|January 23, 2018
Identification of a Novel Positron Emission Tomography (PET) Ligand for Imaging β-Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE-1) in BrainLei Zhang, Laigao Chen, Jason K Dutra, et al.
Journal of Medicinal Chemistry|November 26, 2014
Decreasing the rate of metabolic ketone reduction in the discovery of a clinical acetyl-CoA carboxylase inhibitor for the treatment of diabetesDavid A Griffith, Daniel W Kung, William P Esler, et al.
Bioorganic & Medicinal Chemistry Letters|March 12, 2009
(3,3-Difluoro-pyrrolidin-1-yl)-[(2S,4S)-(4-(4-pyrimidin-2-yl-piperazin-1-yl)-pyrrolidin-2-yl]-methanone: a potent, selective, orally active dipeptidyl peptidase IV inhibitorMark J Ammirati, Kim M Andrews, David D Boyer, et al.
Journal of Medicinal Chemistry|June 30, 2015
Discovery of Highly Isoform Selective Thiazolopiperidine Inhibitors of Phosphoinositide 3-Kinase γPhilip N Collier, David Messersmith, Arnaud Le Tiran, et al.
Nature Communications|October 12, 2016
Chemoproteomic profiling reveals that cathepsin D off-target activity drives ocular toxicity of β-secretase inhibitorsAndrea M Zuhl, Charles E Nolan, Michael A Brodney, et al.
Bioorganic & Medicinal Chemistry Letters|March 12, 2010
Discovery of small molecule isozyme non-specific inhibitors of mammalian acetyl-CoA carboxylase 1 and 2Jeffrey W Corbett, Kevin D Freeman-Cook, Richard Elliott, et al.
Journal of Medicinal Chemistry|September 29, 2017
The Discovery of a Novel Phosphodiesterase (PDE) 4B-Preferring Radioligand for Positron Emission Tomography (PET) ImagingLei Zhang, Laigao Chen, Elizabeth M Beck, et al.
Journal of Medicinal Chemistry|May 26, 2006
cis-2,5-dicyanopyrrolidine inhibitors of dipeptidyl peptidase IV: synthesis and in vitro, in vivo, and X-ray crystallographic characterizationStephen W Wright, Mark J Ammirati, Kim M Andrews, et al.
ACS Medicinal Chemistry Letters|February 20, 2018
Late-Stage Microsomal Oxidation Reduces Drug-Drug Interaction and Identifies Phosphodiesterase 2A Inhibitor PF-06815189Antonia F Stepan, Tuan P Tran, Christopher J Helal, et al.
Bioorganic & Medicinal Chemistry Letters|September 8, 2007
(3R,4S)-4-(2,4,5-Trifluorophenyl)-pyrrolidin-3-ylamine inhibitors of dipeptidyl peptidase IV: synthesis, in vitro, in vivo, and X-ray crystallographic characterizationStephen W Wright, Mark J Ammirati, Kim M Andrews, et al.
Pageof 7

Showing results (51-60 of 70) with videos related to

Sort By:
Pageof 7
Journal of Medicinal Chemistry|January 23, 2018
Identification of a Novel Positron Emission Tomography (PET) Ligand for Imaging β-Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE-1) in BrainLei Zhang, Laigao Chen, Jason K Dutra, et al.
Journal of Medicinal Chemistry|November 26, 2014
Decreasing the rate of metabolic ketone reduction in the discovery of a clinical acetyl-CoA carboxylase inhibitor for the treatment of diabetesDavid A Griffith, Daniel W Kung, William P Esler, et al.
Bioorganic & Medicinal Chemistry Letters|March 12, 2009
(3,3-Difluoro-pyrrolidin-1-yl)-[(2S,4S)-(4-(4-pyrimidin-2-yl-piperazin-1-yl)-pyrrolidin-2-yl]-methanone: a potent, selective, orally active dipeptidyl peptidase IV inhibitorMark J Ammirati, Kim M Andrews, David D Boyer, et al.
Journal of Medicinal Chemistry|June 30, 2015
Discovery of Highly Isoform Selective Thiazolopiperidine Inhibitors of Phosphoinositide 3-Kinase γPhilip N Collier, David Messersmith, Arnaud Le Tiran, et al.
Nature Communications|October 12, 2016
Chemoproteomic profiling reveals that cathepsin D off-target activity drives ocular toxicity of β-secretase inhibitorsAndrea M Zuhl, Charles E Nolan, Michael A Brodney, et al.
Bioorganic & Medicinal Chemistry Letters|March 12, 2010
Discovery of small molecule isozyme non-specific inhibitors of mammalian acetyl-CoA carboxylase 1 and 2Jeffrey W Corbett, Kevin D Freeman-Cook, Richard Elliott, et al.
Journal of Medicinal Chemistry|September 29, 2017
The Discovery of a Novel Phosphodiesterase (PDE) 4B-Preferring Radioligand for Positron Emission Tomography (PET) ImagingLei Zhang, Laigao Chen, Elizabeth M Beck, et al.
Journal of Medicinal Chemistry|May 26, 2006
cis-2,5-dicyanopyrrolidine inhibitors of dipeptidyl peptidase IV: synthesis and in vitro, in vivo, and X-ray crystallographic characterizationStephen W Wright, Mark J Ammirati, Kim M Andrews, et al.
ACS Medicinal Chemistry Letters|February 20, 2018
Late-Stage Microsomal Oxidation Reduces Drug-Drug Interaction and Identifies Phosphodiesterase 2A Inhibitor PF-06815189Antonia F Stepan, Tuan P Tran, Christopher J Helal, et al.
Bioorganic & Medicinal Chemistry Letters|September 8, 2007
(3R,4S)-4-(2,4,5-Trifluorophenyl)-pyrrolidin-3-ylamine inhibitors of dipeptidyl peptidase IV: synthesis, in vitro, in vivo, and X-ray crystallographic characterizationStephen W Wright, Mark J Ammirati, Kim M Andrews, et al.
Pageof 7