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ACS Chemical Neuroscience
|
January 20, 2021
Discovery of Molecular Interactions of the Human Melanocortin-4 Receptor (hMC4R) Asp189 (D189) Amino Acid with the Endogenous G-Protein-Coupled Receptor (GPCR) Antagonist Agouti-Related Protein (AGRP) Provides Insights to AGRP's Inverse Agonist Pharmacology at the hMC4R
Mark D Ericson, Erica M Haslach, Sathya M Schnell, et al.
International Journal of Molecular Sciences
|
June 28, 2023
The Parallel Structure-Activity Relationship Screening of Three Compounds Identifies the Common Agonist Pharmacophore of Pyrrolidine Bis-Cyclic Guanidine Melanocortin-3 Receptor (MC3R) Small-Molecule Ligands
Mark D Ericson, Katie T Freeman, Travis M LaVoi, et al.
International Journal of Obesity (2005)
|
December 31, 2024
Rare variants in the melanocortin 4 receptor gene (MC4R) are associated with abdominal fat and insulin resistance in youth with obesity
Brittany Galuppo, Prabhath Mannam, Jacopo Bonet, et al.
Journal of Medicinal Chemistry
|
May 8, 2023
Correction to "Discovery of Nanomolar Melanocortin-3 Receptor (MC3R)-Selective Small Molecule Pyrrolidine Bis-Cyclic Guanidine Agonist Compounds Via a High Throughput 'Unbiased' Screening Campaign"
Skye R Doering, Katie Freeman, Ginamarie Debevec, et al.
Journal of Medicinal Chemistry
|
April 22, 2021
Discovery of Nanomolar Melanocortin-3 Receptor (MC3R)-Selective Small Molecule Pyrrolidine Bis-Cyclic Guanidine Agonist Compounds Via a High-Throughput "Unbiased" Screening Campaign
Skye R Doering, Katie Freeman, Ginamarie Debevec, et al.
Journal of Medicinal Chemistry
|
January 20, 2025
N-Branched Tricyclic Guanidines as Novel Melanocortin-3 Receptor Agonists and Melanocortin-4 Receptor Antagonists
Nicholas A Weirath, Jonathan W P Zajac, Haley M Donow, et al.
Journal of Medicinal Chemistry
|
October 1, 2021
Functional Mixture-Based Positional Scan Identifies a Library of Antagonist Tetrapeptide Sequences (LAtTeS) with Nanomolar Potency for the Melanocortin-4 Receptor and Equipotent with the Endogenous AGRP(86-132) Antagonist
Mark D Ericson, Skye R Doering, Courtney M Larson, et al.
Journal of Medicinal Chemistry
|
March 27, 2018
Human β-Defensin 1 and β-Defensin 3 (Mouse Ortholog mBD14) Function as Full Endogenous Agonists at Select Melanocortin Receptors
Mark D Ericson, Anamika Singh, Srinivasa R Tala, et al.
Molecular Metabolism
|
March 8, 2021
The melanocortin pathway and energy homeostasis: From discovery to obesity therapy
Giles S H Yeo, Daniela Herrera Moro Chao, Anna-Maria Siegert, et al.
Page
of 9
Search research articles
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Showing results (81-90 of 89) with videos related to
Sort By:
Page
of 9
You have reached the last page of results.
This site can display upto 89 results.
ACS Chemical Neuroscience
|
January 20, 2021
Discovery of Molecular Interactions of the Human Melanocortin-4 Receptor (hMC4R) Asp189 (D189) Amino Acid with the Endogenous G-Protein-Coupled Receptor (GPCR) Antagonist Agouti-Related Protein (AGRP) Provides Insights to AGRP's Inverse Agonist Pharmacology at the hMC4R
Mark D Ericson, Erica M Haslach, Sathya M Schnell, et al.
International Journal of Molecular Sciences
|
June 28, 2023
The Parallel Structure-Activity Relationship Screening of Three Compounds Identifies the Common Agonist Pharmacophore of Pyrrolidine Bis-Cyclic Guanidine Melanocortin-3 Receptor (MC3R) Small-Molecule Ligands
Mark D Ericson, Katie T Freeman, Travis M LaVoi, et al.
International Journal of Obesity (2005)
|
December 31, 2024
Rare variants in the melanocortin 4 receptor gene (MC4R) are associated with abdominal fat and insulin resistance in youth with obesity
Brittany Galuppo, Prabhath Mannam, Jacopo Bonet, et al.
Journal of Medicinal Chemistry
|
May 8, 2023
Correction to "Discovery of Nanomolar Melanocortin-3 Receptor (MC3R)-Selective Small Molecule Pyrrolidine Bis-Cyclic Guanidine Agonist Compounds Via a High Throughput 'Unbiased' Screening Campaign"
Skye R Doering, Katie Freeman, Ginamarie Debevec, et al.
Journal of Medicinal Chemistry
|
April 22, 2021
Discovery of Nanomolar Melanocortin-3 Receptor (MC3R)-Selective Small Molecule Pyrrolidine Bis-Cyclic Guanidine Agonist Compounds Via a High-Throughput "Unbiased" Screening Campaign
Skye R Doering, Katie Freeman, Ginamarie Debevec, et al.
Journal of Medicinal Chemistry
|
January 20, 2025
N-Branched Tricyclic Guanidines as Novel Melanocortin-3 Receptor Agonists and Melanocortin-4 Receptor Antagonists
Nicholas A Weirath, Jonathan W P Zajac, Haley M Donow, et al.
Journal of Medicinal Chemistry
|
October 1, 2021
Functional Mixture-Based Positional Scan Identifies a Library of Antagonist Tetrapeptide Sequences (LAtTeS) with Nanomolar Potency for the Melanocortin-4 Receptor and Equipotent with the Endogenous AGRP(86-132) Antagonist
Mark D Ericson, Skye R Doering, Courtney M Larson, et al.
Journal of Medicinal Chemistry
|
March 27, 2018
Human β-Defensin 1 and β-Defensin 3 (Mouse Ortholog mBD14) Function as Full Endogenous Agonists at Select Melanocortin Receptors
Mark D Ericson, Anamika Singh, Srinivasa R Tala, et al.
Molecular Metabolism
|
March 8, 2021
The melanocortin pathway and energy homeostasis: From discovery to obesity therapy
Giles S H Yeo, Daniela Herrera Moro Chao, Anna-Maria Siegert, et al.
Page
of 9