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Bioorganic & Medicinal Chemistry Letters|January 1, 2010
Benzimidazole- and indole-substituted 1,3'-bipyrrolidine benzamides as histamine H3 receptor antagonistsDerek C Cole, Jonathan L Gross, Thomas A Comery, et al.
Journal of Medicinal Chemistry|October 30, 2014
Discovery and preclinical profiling of 3-[4-(morpholin-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-5-yl]benzonitrile (PF-06447475), a highly potent, selective, brain penetrant, and in vivo active LRRK2 kinase inhibitorJaclyn L Henderson, Bethany L Kormos, Matthew M Hayward, et al.
Cell Chemical Biology|September 11, 2018
Potent α-Synuclein Aggregation Inhibitors, Identified by High-Throughput Screening, Mainly Target the Monomeric StateMartin Kurnik, Cagla Sahin, Camilla Bertel Andersen, et al.
Neurobiology of Disease|November 2, 2018
Development of an aggregate-selective, human-derived α-synuclein antibody BIIB054 that ameliorates disease phenotypes in Parkinson's disease modelsAndreas Weihofen, YuTing Liu, Joseph W Arndt, et al.
Nature Neuroscience|February 26, 2008
Activation of estrogen receptor-beta regulates hippocampal synaptic plasticity and improves memoryFeng Liu, Mark Day, Luis C Muñiz, et al.
European Journal of Pharmacology|October 31, 2006
SB-399885 is a potent, selective 5-HT6 receptor antagonist with cognitive enhancing properties in aged rat water maze and novel object recognition modelsWarren D Hirst, Tania O Stean, Derek C Rogers, et al.
European Journal of Neurology|August 24, 2017
GBA mutations in Parkinson disease: earlier death but similar neuropathological featuresC H Adler, T G Beach, H A Shill, et al.
NPJ Parkinson'S Disease|July 27, 2021
Alpha-synuclein research: defining strategic moves in the battle against Parkinson's diseaseLuis M A Oliveira, Thomas Gasser, Robert Edwards, et al.
NPJ Parkinson'S Disease|May 24, 2022
Beta2-adrenoreceptor agonist clenbuterol produces transient decreases in alpha-synuclein mRNA but no long-term reduction in proteinJoseph R Patterson, Warren D Hirst, Jacob W Howe, et al.
Plos One|June 9, 2021
Decreased glucocerebrosidase activity and substrate accumulation of glycosphingolipids in a novel GBA1 D409V knock-in mouse modelNicole K Polinski, Terina N Martinez, Alexander Gorodinsky, et al.
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