Showing results (371-380 of 390) with videos related to
Sort By:
Pageof 39
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research|May 31, 2024
Oral Estrogen Receptor PROTAC Vepdegestrant (ARV-471) Is Highly Efficacious as Monotherapy and in Combination with CDK4/6 or PI3K/mTOR Pathway Inhibitors in Preclinical ER+ Breast Cancer ModelsSheryl M Gough, John J Flanagan, Jessica Teh, et al.Nature Chemical Biology|June 16, 2015
Catalytic in vivo protein knockdown by small-molecule PROTACsDaniel P Bondeson, Alina Mares, Ian E D Smith, et al.Journal of Medicinal Chemistry|June 27, 2018
Discovery of Potent, Selective, and Peripherally Restricted Pan-Trk Kinase Inhibitors for the Treatment of PainSharan K Bagal, Mark Andrews, Bruce M Bechle, et al.Academic Pediatrics|April 6, 2016
Redesigning Health Care Practices to Address Childhood PovertyArthur H Fierman, Andrew F Beck, Esther K Chung, et al.Cell Stem Cell|August 5, 2022
Dynamic and adaptive cancer stem cell population admixture in colorectal neoplasiaEster Gil Vasquez, Nadia Nasreddin, Gabriel N Valbuena, et al.JCI Insight|June 23, 2025
A TMPRSS6-inhibiting mAb improves disease in a β-thalassemia mouse model and reduces iron in healthy humansHeinrich E Lob, Nikhil Singh, Kusha Mohammadi, et al.Nature Communications|June 9, 2021
Oncogenic BRAF, unrestrained by TGFβ-receptor signalling, drives right-sided colonic tumorigenesisJoshua D G Leach, Nikola Vlahov, Petros Tsantoulis, et al.Nature|June 3, 2021
NOTUM from Apc-mutant cells biases clonal competition to initiate cancerDustin J Flanagan, Nalle Pentinmikko, Kalle Luopajärvi, et al.Nature Communications|December 8, 2022
Epithelial TGFβ engages growth-factor signalling to circumvent apoptosis and drive intestinal tumourigenesis with aggressive featuresDustin J Flanagan, Raheleh Amirkhah, David F Vincent, et al.Cancer Discovery|December 17, 2020
MNK Inhibition Sensitizes KRAS-Mutant Colorectal Cancer to mTORC1 Inhibition by Reducing eIF4E Phosphorylation and c-MYC ExpressionJohn R P Knight, Constantinos Alexandrou, George L Skalka, et al.Pageof 39