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Drug Metabolism and Disposition: the Biological Fate of Chemicals
|
November 1, 1996
Role of cytochrome P450 in oxazaphosphorine metabolism. Deactivation via N-dechloroethylation and activation via 4-hydroxylation catalyzed by distinct subsets of rat liver cytochromes P450
L Yu, D J Waxman
Analytical Biochemistry
|
August 24, 1999
High-performance liquid chromatographic-fluorescent method to determine chloroacetaldehyde, a neurotoxic metabolite of the anticancer drug ifosfamide, in plasma and in liver microsomal incubations
Z Huang, D J Waxman
Cancer Research
|
February 1, 1995
Intratumoral activation and enhanced chemotherapeutic effect of oxazaphosphorines following cytochrome P-450 gene transfer: development of a combined chemotherapy/cancer gene therapy strategy
L Chen, D J Waxman
Cancer Gene Therapy
|
August 11, 2001
Modulation of cyclophosphamide-based cytochrome P450 gene therapy using liver P450 inhibitors
Z Huang, D J Waxman
The Journal of Pharmacology and Experimental Therapeutics
|
September 1, 1995
Complete reversal by thaliblastine of 490-fold adriamycin resistance in multidrug-resistant (MDR) human breast cancer cells. Evidence that multiple biochemical changes in MDR cells need not correspond to multiple functional determinants for drug resistance
G Chen, D J Waxman
Archives of Biochemistry and Biophysics
|
August 1, 1987
Human liver folylpolyglutamate synthetase: biochemical characterization and interactions with folates and folate antagonists
L Clarke, D J Waxman
Cancer Research
|
May 1, 1989
Oxidative metabolism of cyclophosphamide: identification of the hepatic monooxygenase catalysts of drug activation
L Clarke, D J Waxman
Cancer Research
|
June 5, 2001
Frequent, moderate-dose cyclophosphamide administration improves the efficacy of cytochrome P-450/cytochrome P-450 reductase-based cancer gene therapy
Y Jounaidi, D J Waxman
Biochemical Pharmacology
|
May 26, 1995
Identification of glutathione S-transferase as a determinant of 4-hydroperoxycyclophosphamide resistance in human breast cancer cells
G Chen, D J Waxman
Molecular Pharmacology
|
November 28, 2001
Cyclophosphamide induces caspase 9-dependent apoptosis in 9L tumor cells
P S Schwartz, D J Waxman
Page
of 19
Search research articles
Search
Showing results (11-20 of 182) with videos related to
Sort By:
Page
of 19
Drug Metabolism and Disposition: the Biological Fate of Chemicals
|
November 1, 1996
Role of cytochrome P450 in oxazaphosphorine metabolism. Deactivation via N-dechloroethylation and activation via 4-hydroxylation catalyzed by distinct subsets of rat liver cytochromes P450
L Yu, D J Waxman
Analytical Biochemistry
|
August 24, 1999
High-performance liquid chromatographic-fluorescent method to determine chloroacetaldehyde, a neurotoxic metabolite of the anticancer drug ifosfamide, in plasma and in liver microsomal incubations
Z Huang, D J Waxman
Cancer Research
|
February 1, 1995
Intratumoral activation and enhanced chemotherapeutic effect of oxazaphosphorines following cytochrome P-450 gene transfer: development of a combined chemotherapy/cancer gene therapy strategy
L Chen, D J Waxman
Cancer Gene Therapy
|
August 11, 2001
Modulation of cyclophosphamide-based cytochrome P450 gene therapy using liver P450 inhibitors
Z Huang, D J Waxman
The Journal of Pharmacology and Experimental Therapeutics
|
September 1, 1995
Complete reversal by thaliblastine of 490-fold adriamycin resistance in multidrug-resistant (MDR) human breast cancer cells. Evidence that multiple biochemical changes in MDR cells need not correspond to multiple functional determinants for drug resistance
G Chen, D J Waxman
Archives of Biochemistry and Biophysics
|
August 1, 1987
Human liver folylpolyglutamate synthetase: biochemical characterization and interactions with folates and folate antagonists
L Clarke, D J Waxman
Cancer Research
|
May 1, 1989
Oxidative metabolism of cyclophosphamide: identification of the hepatic monooxygenase catalysts of drug activation
L Clarke, D J Waxman
Cancer Research
|
June 5, 2001
Frequent, moderate-dose cyclophosphamide administration improves the efficacy of cytochrome P-450/cytochrome P-450 reductase-based cancer gene therapy
Y Jounaidi, D J Waxman
Biochemical Pharmacology
|
May 26, 1995
Identification of glutathione S-transferase as a determinant of 4-hydroperoxycyclophosphamide resistance in human breast cancer cells
G Chen, D J Waxman
Molecular Pharmacology
|
November 28, 2001
Cyclophosphamide induces caspase 9-dependent apoptosis in 9L tumor cells
P S Schwartz, D J Waxman
Page
of 19