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D Penning

Showing results (21-30 of 50) with videos related to

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Bioorganic & Medicinal Chemistry Letters|February 14, 2012
Aminopyrimidinone cdc7 kinase inhibitorsKeith W Woods, Chunqiu Lai, Julie M Miyashiro, et al.
Nature|December 19, 1996
Structural basis for selective inhibition of cyclooxygenase-2 by anti-inflammatory agentsR G Kurumbail, A M Stevens, J K Gierse, et al.
Bioorganic & Medicinal Chemistry Letters|September 16, 2008
Isoxazolo[3,4-b]quinoline-3,4(1H,9H)-diones as unique, potent and selective inhibitors for Pim-1 and Pim-2 kinases: chemistry, biological activities, and molecular modelingYunsong Tong, Kent D Stewart, Sheela Thomas, et al.
Bioorganic & Medicinal Chemistry Letters|October 30, 2012
Hit to Lead optimization of a novel class of squarate-containing polo-like kinases inhibitorsQingwei Zhang, Zhiren Xia, Michael J Mitten, et al.
ACS Medicinal Chemistry Letters|January 16, 2015
Pyrimidine-based tricyclic molecules as potent and orally efficacious inhibitors of wee1 kinaseYunsong Tong, Maricel Torrent, Alan S Florjancic, et al.
Bioorganic & Medicinal Chemistry Letters|July 1, 2008
Synthesis and SAR of novel, potent and orally bioavailable benzimidazole inhibitors of poly(ADP-ribose) polymerase (PARP) with a quaternary methylene-amino substituentGui-Dong Zhu, Viraj B Gandhi, Jianchun Gong, et al.
Bioorganic & Medicinal Chemistry|July 7, 2012
Discovery and SAR of orally efficacious tetrahydropyridopyridazinone PARP inhibitors for the treatment of cancerGui-Dong Zhu, Jianchun Gong, Viraj B Gandhi, et al.
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research|November 26, 2009
ABT-888 confers broad in vivo activity in combination with temozolomide in diverse tumorsJoann P Palma, Yi-Chun Wang, Luis E Rodriguez, et al.
Journal of Medicinal Chemistry|January 16, 2009
Discovery of the Poly(ADP-ribose) polymerase (PARP) inhibitor 2-[(R)-2-methylpyrrolidin-2-yl]-1H-benzimidazole-4-carboxamide (ABT-888) for the treatment of cancerThomas D Penning, Gui-Dong Zhu, Viraj B Gandhi, et al.
Journal of Medicinal Chemistry|October 22, 2009
Discovery of 3H-benzo[4,5]thieno[3,2-d]pyrimidin-4-ones as potent, highly selective, and orally bioavailable inhibitors of the human protooncogene proviral insertion site in moloney murine leukemia virus (PIM) kinasesZhi-Fu Tao, Lisa A Hasvold, Joel D Leverson, et al.
Pageof 5

Showing results (21-30 of 50) with videos related to

Sort By:
Pageof 5
Bioorganic & Medicinal Chemistry Letters|February 14, 2012
Aminopyrimidinone cdc7 kinase inhibitorsKeith W Woods, Chunqiu Lai, Julie M Miyashiro, et al.
Nature|December 19, 1996
Structural basis for selective inhibition of cyclooxygenase-2 by anti-inflammatory agentsR G Kurumbail, A M Stevens, J K Gierse, et al.
Bioorganic & Medicinal Chemistry Letters|September 16, 2008
Isoxazolo[3,4-b]quinoline-3,4(1H,9H)-diones as unique, potent and selective inhibitors for Pim-1 and Pim-2 kinases: chemistry, biological activities, and molecular modelingYunsong Tong, Kent D Stewart, Sheela Thomas, et al.
Bioorganic & Medicinal Chemistry Letters|October 30, 2012
Hit to Lead optimization of a novel class of squarate-containing polo-like kinases inhibitorsQingwei Zhang, Zhiren Xia, Michael J Mitten, et al.
ACS Medicinal Chemistry Letters|January 16, 2015
Pyrimidine-based tricyclic molecules as potent and orally efficacious inhibitors of wee1 kinaseYunsong Tong, Maricel Torrent, Alan S Florjancic, et al.
Bioorganic & Medicinal Chemistry Letters|July 1, 2008
Synthesis and SAR of novel, potent and orally bioavailable benzimidazole inhibitors of poly(ADP-ribose) polymerase (PARP) with a quaternary methylene-amino substituentGui-Dong Zhu, Viraj B Gandhi, Jianchun Gong, et al.
Bioorganic & Medicinal Chemistry|July 7, 2012
Discovery and SAR of orally efficacious tetrahydropyridopyridazinone PARP inhibitors for the treatment of cancerGui-Dong Zhu, Jianchun Gong, Viraj B Gandhi, et al.
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research|November 26, 2009
ABT-888 confers broad in vivo activity in combination with temozolomide in diverse tumorsJoann P Palma, Yi-Chun Wang, Luis E Rodriguez, et al.
Journal of Medicinal Chemistry|January 16, 2009
Discovery of the Poly(ADP-ribose) polymerase (PARP) inhibitor 2-[(R)-2-methylpyrrolidin-2-yl]-1H-benzimidazole-4-carboxamide (ABT-888) for the treatment of cancerThomas D Penning, Gui-Dong Zhu, Viraj B Gandhi, et al.
Journal of Medicinal Chemistry|October 22, 2009
Discovery of 3H-benzo[4,5]thieno[3,2-d]pyrimidin-4-ones as potent, highly selective, and orally bioavailable inhibitors of the human protooncogene proviral insertion site in moloney murine leukemia virus (PIM) kinasesZhi-Fu Tao, Lisa A Hasvold, Joel D Leverson, et al.
Pageof 5