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D Penning

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Bioorganic & Medicinal Chemistry Letters|April 20, 2006
Synthesis of pyrazoles and isoxazoles as potent alpha(v)beta3 receptor antagonistsThomas D Penning, Albert Khilevich, Barbara B Chen, et al.
Journal of Medicinal Chemistry|March 27, 2010
Optimization of phenyl-substituted benzimidazole carboxamide poly(ADP-ribose) polymerase inhibitors: identification of (S)-2-(2-fluoro-4-(pyrrolidin-2-yl)phenyl)-1H-benzimidazole-4-carboxamide (A-966492), a highly potent and efficacious inhibitorThomas D Penning, Gui-Dong Zhu, Jianchun Gong, et al.
Bioorganic & Medicinal Chemistry|June 11, 2008
Discovery and SAR of 2-(1-propylpiperidin-4-yl)-1H-benzimidazole-4-carboxamide: A potent inhibitor of poly(ADP-ribose) polymerase (PARP) for the treatment of cancerThomas D Penning, Gui-Dong Zhu, Viraj B Gandhi, et al.
Journal of Medicinal Chemistry|May 26, 2007
Syntheses of potent, selective, and orally bioavailable indazole-pyridine series of protein kinase B/Akt inhibitors with reduced hypotensionGui-Dong Zhu, Viraj B Gandhi, Jianchun Gong, et al.
Journal of Medicinal Chemistry|April 25, 1997
Synthesis and biological evaluation of the 1,5-diarylpyrazole class of cyclooxygenase-2 inhibitors: identification of 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benze nesulfonamide (SC-58635, celecoxib)T D Penning, J J Talley, S R Bertenshaw, et al.
Journal of Medicinal Chemistry|October 1, 2024
Discovery of Potent Azetidine-Benzoxazole MerTK Inhibitors with <i>In Vivo</i> Target EngagementRobin R Frey, Navendu Jana, Jacob V Gorman, et al.
Journal of Medicinal Chemistry|February 26, 2000
Structure-activity relationship studies on 1-[2-(4-Phenylphenoxy)ethyl]pyrrolidine (SC-22716), a potent inhibitor of leukotriene A(4) (LTA(4)) hydrolaseT D Penning, N S Chandrakumar, B B Chen, et al.
Bioorganic & Medicinal Chemistry Letters|November 22, 2005
Convergent, parallel synthesis of a series of beta-substituted 1,2,4-oxadiazole butanoic acids as potent and selective alpha(v)beta3 receptor antagonistsMark L Boys, Lori A Schretzman, Nizal S Chandrakumar, et al.
Journal of Medicinal Chemistry|September 16, 2024
Discovery of A-910, a Highly Potent and Orally Bioavailable Dual MerTK/Axl-Selective Tyrosine Kinase InhibitorYiyun Yu, Miyeon Jang, Julie Miyashiro, et al.
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research|May 3, 2007
ABT-888, an orally active poly(ADP-ribose) polymerase inhibitor that potentiates DNA-damaging agents in preclinical tumor modelsCherrie K Donawho, Yan Luo, Yanping Luo, et al.
Pageof 5

Showing results (41-50 of 50) with videos related to

Sort By:
Pageof 5
You have reached the last page of results.This site can display upto 50 results.
Bioorganic & Medicinal Chemistry Letters|April 20, 2006
Synthesis of pyrazoles and isoxazoles as potent alpha(v)beta3 receptor antagonistsThomas D Penning, Albert Khilevich, Barbara B Chen, et al.
Journal of Medicinal Chemistry|March 27, 2010
Optimization of phenyl-substituted benzimidazole carboxamide poly(ADP-ribose) polymerase inhibitors: identification of (S)-2-(2-fluoro-4-(pyrrolidin-2-yl)phenyl)-1H-benzimidazole-4-carboxamide (A-966492), a highly potent and efficacious inhibitorThomas D Penning, Gui-Dong Zhu, Jianchun Gong, et al.
Bioorganic & Medicinal Chemistry|June 11, 2008
Discovery and SAR of 2-(1-propylpiperidin-4-yl)-1H-benzimidazole-4-carboxamide: A potent inhibitor of poly(ADP-ribose) polymerase (PARP) for the treatment of cancerThomas D Penning, Gui-Dong Zhu, Viraj B Gandhi, et al.
Journal of Medicinal Chemistry|May 26, 2007
Syntheses of potent, selective, and orally bioavailable indazole-pyridine series of protein kinase B/Akt inhibitors with reduced hypotensionGui-Dong Zhu, Viraj B Gandhi, Jianchun Gong, et al.
Journal of Medicinal Chemistry|April 25, 1997
Synthesis and biological evaluation of the 1,5-diarylpyrazole class of cyclooxygenase-2 inhibitors: identification of 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benze nesulfonamide (SC-58635, celecoxib)T D Penning, J J Talley, S R Bertenshaw, et al.
Journal of Medicinal Chemistry|October 1, 2024
Discovery of Potent Azetidine-Benzoxazole MerTK Inhibitors with <i>In Vivo</i> Target EngagementRobin R Frey, Navendu Jana, Jacob V Gorman, et al.
Journal of Medicinal Chemistry|February 26, 2000
Structure-activity relationship studies on 1-[2-(4-Phenylphenoxy)ethyl]pyrrolidine (SC-22716), a potent inhibitor of leukotriene A(4) (LTA(4)) hydrolaseT D Penning, N S Chandrakumar, B B Chen, et al.
Bioorganic & Medicinal Chemistry Letters|November 22, 2005
Convergent, parallel synthesis of a series of beta-substituted 1,2,4-oxadiazole butanoic acids as potent and selective alpha(v)beta3 receptor antagonistsMark L Boys, Lori A Schretzman, Nizal S Chandrakumar, et al.
Journal of Medicinal Chemistry|September 16, 2024
Discovery of A-910, a Highly Potent and Orally Bioavailable Dual MerTK/Axl-Selective Tyrosine Kinase InhibitorYiyun Yu, Miyeon Jang, Julie Miyashiro, et al.
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research|May 3, 2007
ABT-888, an orally active poly(ADP-ribose) polymerase inhibitor that potentiates DNA-damaging agents in preclinical tumor modelsCherrie K Donawho, Yan Luo, Yanping Luo, et al.
Pageof 5