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D Pennington

Showing results (81-90 of 95) with videos related to

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Journal of Medicinal Chemistry|March 12, 2014
Small molecule disruptors of the glucokinase-glucokinase regulatory protein interaction: 3. Structure-activity relationships within the aryl carbinol region of the N-arylsulfonamido-N'-arylpiperazine seriesNobuko Nishimura, Mark H Norman, Longbin Liu, et al.
Journal of Medicinal Chemistry|January 17, 1997
Structure-activity relationships of selective estrogen receptor modulators: modifications to the 2-arylbenzothiophene core of raloxifeneT A Grese, S Cho, D R Finley, et al.
Microbiology Resource Announcements|February 8, 2020
Isolation and Whole-Genome Sequencing of 12 Mushroom-Associated Bacterial Strains: an Inquiry-Based Laboratory Exercise in a Genomics Course at the Rochester Institute of TechnologyNarayan H Wong, Andrew J Rosato, Yara M Rose, et al.
ACS Medicinal Chemistry Letters|June 6, 2014
4-Methoxy-N-[2-(trifluoromethyl)biphenyl-4-ylcarbamoyl]nicotinamide: A Potent and Selective Agonist of S1P1Lewis D Pennington, Kelvin K C Sham, Alexander J Pickrell, et al.
ACS Medicinal Chemistry Letters|June 6, 2014
Optimization of a Potent, Orally Active S1P1 Agonist Containing a Quinolinone CorePaul E Harrington, Michael D Croghan, Christopher Fotsch, et al.
Bioorganic & Medicinal Chemistry Letters|November 23, 2011
Quinolinone-based agonists of S1P₁: use of a N-scan SAR strategy to optimize in vitro and in vivo activityLewis D Pennington, Michael D Croghan, Kelvin K C Sham, et al.
Journal of Medicinal Chemistry|January 11, 2014
Small molecule disruptors of the glucokinase-glucokinase regulatory protein interaction: 1. Discovery of a novel tool compound for in vivo proof-of-conceptKate S Ashton, Kristin L Andrews, Marian C Bryan, et al.
Journal of Medicinal Chemistry|January 11, 2014
Small molecule disruptors of the glucokinase-glucokinase regulatory protein interaction: 2. Leveraging structure-based drug design to identify analogues with improved pharmacokinetic profilesDavid J St Jean, Kate S Ashton, Michael D Bartberger, et al.
Nature|November 15, 2013
Antidiabetic effects of glucokinase regulatory protein small-molecule disruptorsDavid J Lloyd, David J St Jean, Robert J M Kurzeja, et al.
Journal of Medicinal Chemistry|November 10, 2015
Discovery and Structure-Guided Optimization of Diarylmethanesulfonamide Disrupters of Glucokinase-Glucokinase Regulatory Protein (GK-GKRP) Binding: Strategic Use of a N → S (nN → σ*S-X) Interaction for Conformational ConstraintLewis D Pennington, Michael D Bartberger, Michael D Croghan, et al.
Pageof 10

Showing results (81-90 of 95) with videos related to

Sort By:
Pageof 10
Journal of Medicinal Chemistry|March 12, 2014
Small molecule disruptors of the glucokinase-glucokinase regulatory protein interaction: 3. Structure-activity relationships within the aryl carbinol region of the N-arylsulfonamido-N'-arylpiperazine seriesNobuko Nishimura, Mark H Norman, Longbin Liu, et al.
Journal of Medicinal Chemistry|January 17, 1997
Structure-activity relationships of selective estrogen receptor modulators: modifications to the 2-arylbenzothiophene core of raloxifeneT A Grese, S Cho, D R Finley, et al.
Microbiology Resource Announcements|February 8, 2020
Isolation and Whole-Genome Sequencing of 12 Mushroom-Associated Bacterial Strains: an Inquiry-Based Laboratory Exercise in a Genomics Course at the Rochester Institute of TechnologyNarayan H Wong, Andrew J Rosato, Yara M Rose, et al.
ACS Medicinal Chemistry Letters|June 6, 2014
4-Methoxy-N-[2-(trifluoromethyl)biphenyl-4-ylcarbamoyl]nicotinamide: A Potent and Selective Agonist of S1P1Lewis D Pennington, Kelvin K C Sham, Alexander J Pickrell, et al.
ACS Medicinal Chemistry Letters|June 6, 2014
Optimization of a Potent, Orally Active S1P1 Agonist Containing a Quinolinone CorePaul E Harrington, Michael D Croghan, Christopher Fotsch, et al.
Bioorganic & Medicinal Chemistry Letters|November 23, 2011
Quinolinone-based agonists of S1P₁: use of a N-scan SAR strategy to optimize in vitro and in vivo activityLewis D Pennington, Michael D Croghan, Kelvin K C Sham, et al.
Journal of Medicinal Chemistry|January 11, 2014
Small molecule disruptors of the glucokinase-glucokinase regulatory protein interaction: 1. Discovery of a novel tool compound for in vivo proof-of-conceptKate S Ashton, Kristin L Andrews, Marian C Bryan, et al.
Journal of Medicinal Chemistry|January 11, 2014
Small molecule disruptors of the glucokinase-glucokinase regulatory protein interaction: 2. Leveraging structure-based drug design to identify analogues with improved pharmacokinetic profilesDavid J St Jean, Kate S Ashton, Michael D Bartberger, et al.
Nature|November 15, 2013
Antidiabetic effects of glucokinase regulatory protein small-molecule disruptorsDavid J Lloyd, David J St Jean, Robert J M Kurzeja, et al.
Journal of Medicinal Chemistry|November 10, 2015
Discovery and Structure-Guided Optimization of Diarylmethanesulfonamide Disrupters of Glucokinase-Glucokinase Regulatory Protein (GK-GKRP) Binding: Strategic Use of a N → S (nN → σ*S-X) Interaction for Conformational ConstraintLewis D Pennington, Michael D Bartberger, Michael D Croghan, et al.
Pageof 10