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Biochemistry|September 5, 2013
Enzyme-dependent lysine deprotonation in EZH2 catalysisD Randal Kipp, Christopher M Quinn, Pascal D FortinBiochemistry|August 9, 2012
Constrained bonding environment in the Michaelis complex of Trypanosoma cruzi uridine phosphorylaseRafael G Silva, D Randal Kipp, Vern L SchrammJournal of the American Chemical Society|November 9, 2011
Mass-dependent bond vibrational dynamics influence catalysis by HIV-1 proteaseD Randal Kipp, Rafael G Silva, Vern L SchrammProceedings of the National Academy of Sciences of the United States of America|April 12, 2012
Transition states of native and drug-resistant HIV-1 protease are the sameD Randal Kipp, Jennifer S Hirschi, Aya Wakata, et al.The Journal of Biological Chemistry|November 13, 2007
Suppression of in vivo beta-amyloid peptide toxicity by overexpression of the HSP-16.2 small chaperone proteinVirginia Fonte, D Randal Kipp, John Yerg, et al.Chemistry & Biology|December 30, 2014
The novolactone natural product disrupts the allosteric regulation of Hsp70A Quamrul Hassan, Christina A Kirby, Wenlai Zhou, et al.Journal of Medicinal Chemistry|September 29, 2023
Identification of GDC-1971 (RLY-1971), a SHP2 Inhibitor Designed for the Treatment of Solid TumorsAlexander M Taylor, Bret R Williams, Fabrizio Giordanetto, et al.Science (New York, N.Y.)|February 26, 2016
Disordered methionine metabolism in MTAP/CDKN2A-deleted cancers leads to dependence on PRMT5Konstantinos J Mavrakis, E Robert McDonald, Michael R Schlabach, et al.Cancer Discovery|November 2, 2023
Discovery and Clinical Proof-of-Concept of RLY-2608, a First-in-Class Mutant-Selective Allosteric PI3Kα Inhibitor That Decouples Antitumor Activity from HyperinsulinemiaAndreas Varkaris, Ermira Pazolli, Hakan Gunaydin, et al.Pageof 1