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Proceedings of the National Academy of Sciences of the United States of America
|
February 5, 2024
Acceleration of infectious disease drug discovery and development using a humanized model of drug metabolism
A Kenneth MacLeod, Kevin-Sebastien Coquelin, Leticia Huertas, et al.
Blood Purification
|
September 13, 2021
Adjunct Use of Continuous Renal Replacement Therapy with Extracorporeal Membrane Oxygenation Achieves Negative Fluid Balance and Enhances Oxygenation Which Improves Survival in Critically Ill Patients without Kidney Failure
Jason M Thomas, David N Dado, Anthony P Basel, et al.
Chemmedchem
|
September 24, 2015
Development of Small-Molecule Trypanosoma brucei N-Myristoyltransferase Inhibitors: Discovery and Optimisation of a Novel Binding Mode
Daniel Spinks, Victoria Smith, Stephen Thompson, et al.
Malaria Journal
|
June 8, 2011
Central nervous system exposure of next generation quinoline methanols is reduced relative to mefloquine after intravenous dosing in mice
Geoffrey S Dow, Erin Milner, Ian Bathurst, et al.
ACS Medicinal Chemistry Letters
|
January 24, 2014
Discovery of β2 Adrenergic Receptor Ligands Using Biosensor Fragment Screening of Tagged Wild-Type Receptor
Tonia Aristotelous, Seungkirl Ahn, Arun K Shukla, et al.
Journal of Medicinal Chemistry
|
September 13, 2018
A Molecular Hybridization Approach for the Design of Potent, Highly Selective, and Brain-Penetrant N-Myristoyltransferase Inhibitors
Justin R Harrison, Stephen Brand, Victoria Smith, et al.
The Journal of Infectious Diseases
|
February 13, 2026
Variable Staphylothrombin Activity in Staphylococcus aureus Bloodstream Infections
Gregory L Damhorst, Madeline J Boulis, Elizabeth B Nelson, et al.
ACS Chemical Biology
|
June 18, 2025
High-Throughput Screening of Potent Drug-like Molecules Targeting 17β-HSD10 for the Treatment of Alzheimer's Disease and Cancer
Laura Aitken, Gemma Baillie, Andrew Pannifer, et al.
Communications Biology
|
August 3, 2019
A brain-permeable inhibitor of the neurodegenerative disease target kynurenine 3-monooxygenase prevents accumulation of neurotoxic metabolites
Shaowei Zhang, Michiyo Sakuma, Girdhar S Deora, et al.
Nature Communications
|
October 23, 2020
Targeting N-myristoylation for therapy of B-cell lymphomas
Erwan Beauchamp, Megan C Yap, Aishwarya Iyer, et al.
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Search research articles
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Showing results (631-640 of 718) with videos related to
Sort By:
Page
of 72
Proceedings of the National Academy of Sciences of the United States of America
|
February 5, 2024
Acceleration of infectious disease drug discovery and development using a humanized model of drug metabolism
A Kenneth MacLeod, Kevin-Sebastien Coquelin, Leticia Huertas, et al.
Blood Purification
|
September 13, 2021
Adjunct Use of Continuous Renal Replacement Therapy with Extracorporeal Membrane Oxygenation Achieves Negative Fluid Balance and Enhances Oxygenation Which Improves Survival in Critically Ill Patients without Kidney Failure
Jason M Thomas, David N Dado, Anthony P Basel, et al.
Chemmedchem
|
September 24, 2015
Development of Small-Molecule Trypanosoma brucei N-Myristoyltransferase Inhibitors: Discovery and Optimisation of a Novel Binding Mode
Daniel Spinks, Victoria Smith, Stephen Thompson, et al.
Malaria Journal
|
June 8, 2011
Central nervous system exposure of next generation quinoline methanols is reduced relative to mefloquine after intravenous dosing in mice
Geoffrey S Dow, Erin Milner, Ian Bathurst, et al.
ACS Medicinal Chemistry Letters
|
January 24, 2014
Discovery of β2 Adrenergic Receptor Ligands Using Biosensor Fragment Screening of Tagged Wild-Type Receptor
Tonia Aristotelous, Seungkirl Ahn, Arun K Shukla, et al.
Journal of Medicinal Chemistry
|
September 13, 2018
A Molecular Hybridization Approach for the Design of Potent, Highly Selective, and Brain-Penetrant N-Myristoyltransferase Inhibitors
Justin R Harrison, Stephen Brand, Victoria Smith, et al.
The Journal of Infectious Diseases
|
February 13, 2026
Variable Staphylothrombin Activity in Staphylococcus aureus Bloodstream Infections
Gregory L Damhorst, Madeline J Boulis, Elizabeth B Nelson, et al.
ACS Chemical Biology
|
June 18, 2025
High-Throughput Screening of Potent Drug-like Molecules Targeting 17β-HSD10 for the Treatment of Alzheimer's Disease and Cancer
Laura Aitken, Gemma Baillie, Andrew Pannifer, et al.
Communications Biology
|
August 3, 2019
A brain-permeable inhibitor of the neurodegenerative disease target kynurenine 3-monooxygenase prevents accumulation of neurotoxic metabolites
Shaowei Zhang, Michiyo Sakuma, Girdhar S Deora, et al.
Nature Communications
|
October 23, 2020
Targeting N-myristoylation for therapy of B-cell lymphomas
Erwan Beauchamp, Megan C Yap, Aishwarya Iyer, et al.
Page
of 72