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Biochemistry
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September 21, 1993
Characterization of the non-heme iron center of human 5-lipoxygenase by electron paramagnetic resonance, fluorescence, and ultraviolet-visible spectroscopy: redox cycling between ferrous and ferric states
N D Chasteen, J K Grady, K I Skorey, et al.
Journal of Medicinal Chemistry
|
September 17, 1993
Substituted thiopyrano[2,3,4-c,d]indoles as potent, selective, and orally active inhibitors of 5-lipoxygenase. Synthesis and biological evaluation of L-691,816
J H Hutchinson, D Riendeau, C Brideau, et al.
American Journal of Physiology. Renal Physiology
|
November 13, 2001
Urogenital distribution of a mouse membrane-associated prostaglandin E(2) synthase
Y Guan, Y Zhang, A Schneider, et al.
Bioorganic & Medicinal Chemistry Letters
|
July 9, 1999
2-heterosubstituted-3-(4-methylsulfonyl)phenyl-5-trifluoromethyl pyridines as selective and orally active cyclooxygenase-2 inhibitors
D Dubé, C Brideau, D Deschênes, et al.
The Journal of Biological Chemistry
|
June 3, 1994
Arachidonyl trifluoromethyl ketone, a potent inhibitor of 85-kDa phospholipase A2, blocks production of arachidonate and 12-hydroxyeicosatetraenoic acid by calcium ionophore-challenged platelets
D Riendeau, J Guay, P K Weech, et al.
Journal of Medicinal Chemistry
|
April 15, 1994
Thiopyrano[2,3,4-cd]indoles as 5-lipoxygenase inhibitors: synthesis, biological profile, and resolution of 2-[2-[1-(4-chlorobenzyl)-4-methyl-6-[(5-phenylpyridin-2-yl)methoxy]-4,5 -dihydro-1H-thiopyrano[2,3,4-cd]indol-2-yl]ethoxy]butanoic acid
J H Hutchinson, D Riendeau, C Brideau, et al.
Bioorganic & Medicinal Chemistry Letters
|
May 1, 2001
In vitro metabolism considerations, including activity testing of metabolites, in the discovery and selection of the COX-2 inhibitor etoricoxib (MK-0663)
N Chauret, J A Yergey, C Brideau, et al.
Journal of Medicinal Chemistry
|
April 3, 1992
Development of 2,3-dihydro-6-(3-phenoxypropyl)-2-(2-phenylethyl)-5-benzofuranol (L-670,630) as a potent and orally active inhibitor of 5-lipoxygenase
C K Lau, P C Bélanger, C Dufresne, et al.
Journal of Medicinal Chemistry
|
January 5, 2001
Novel, nonpeptidic cyanamides as potent and reversible inhibitors of human cathepsins K and L
J P Falgueyret, R M Oballa, O Okamoto, et al.
Journal of Medicinal Chemistry
|
February 18, 1994
Naphthalenic lignan lactones as selective, nonredox 5-lipoxygenase inhibitors. Synthesis and biological activity of (methoxyalkyl)thiazole and methoxytetrahydropyran hybrids
Y Ducharme, C Brideau, D Dubé, et al.
Page
of 8
Search research articles
Search
Showing results (51-60 of 78) with videos related to
Sort By:
Page
of 8
Biochemistry
|
September 21, 1993
Characterization of the non-heme iron center of human 5-lipoxygenase by electron paramagnetic resonance, fluorescence, and ultraviolet-visible spectroscopy: redox cycling between ferrous and ferric states
N D Chasteen, J K Grady, K I Skorey, et al.
Journal of Medicinal Chemistry
|
September 17, 1993
Substituted thiopyrano[2,3,4-c,d]indoles as potent, selective, and orally active inhibitors of 5-lipoxygenase. Synthesis and biological evaluation of L-691,816
J H Hutchinson, D Riendeau, C Brideau, et al.
American Journal of Physiology. Renal Physiology
|
November 13, 2001
Urogenital distribution of a mouse membrane-associated prostaglandin E(2) synthase
Y Guan, Y Zhang, A Schneider, et al.
Bioorganic & Medicinal Chemistry Letters
|
July 9, 1999
2-heterosubstituted-3-(4-methylsulfonyl)phenyl-5-trifluoromethyl pyridines as selective and orally active cyclooxygenase-2 inhibitors
D Dubé, C Brideau, D Deschênes, et al.
The Journal of Biological Chemistry
|
June 3, 1994
Arachidonyl trifluoromethyl ketone, a potent inhibitor of 85-kDa phospholipase A2, blocks production of arachidonate and 12-hydroxyeicosatetraenoic acid by calcium ionophore-challenged platelets
D Riendeau, J Guay, P K Weech, et al.
Journal of Medicinal Chemistry
|
April 15, 1994
Thiopyrano[2,3,4-cd]indoles as 5-lipoxygenase inhibitors: synthesis, biological profile, and resolution of 2-[2-[1-(4-chlorobenzyl)-4-methyl-6-[(5-phenylpyridin-2-yl)methoxy]-4,5 -dihydro-1H-thiopyrano[2,3,4-cd]indol-2-yl]ethoxy]butanoic acid
J H Hutchinson, D Riendeau, C Brideau, et al.
Bioorganic & Medicinal Chemistry Letters
|
May 1, 2001
In vitro metabolism considerations, including activity testing of metabolites, in the discovery and selection of the COX-2 inhibitor etoricoxib (MK-0663)
N Chauret, J A Yergey, C Brideau, et al.
Journal of Medicinal Chemistry
|
April 3, 1992
Development of 2,3-dihydro-6-(3-phenoxypropyl)-2-(2-phenylethyl)-5-benzofuranol (L-670,630) as a potent and orally active inhibitor of 5-lipoxygenase
C K Lau, P C Bélanger, C Dufresne, et al.
Journal of Medicinal Chemistry
|
January 5, 2001
Novel, nonpeptidic cyanamides as potent and reversible inhibitors of human cathepsins K and L
J P Falgueyret, R M Oballa, O Okamoto, et al.
Journal of Medicinal Chemistry
|
February 18, 1994
Naphthalenic lignan lactones as selective, nonredox 5-lipoxygenase inhibitors. Synthesis and biological activity of (methoxyalkyl)thiazole and methoxytetrahydropyran hybrids
Y Ducharme, C Brideau, D Dubé, et al.
Page
of 8