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Scientific Reports|November 7, 2022
The NOGO receptor NgR2, a novel αVβ3 integrin effector, induces neuroendocrine differentiation in prostate cancerFabio Quaglia, Shiv Ram Krishn, Khalid Sossey-Alaoui, et al.Nature Immunology|August 5, 2020
ILC2-driven innate immune checkpoint mechanism antagonizes NK cell antimetastatic function in the lungMartijn J Schuijs, Shaun Png, Arianne C Richard, et al.JAMA Network Open|November 15, 2024
Obstetric Life Support Education for Maternal Cardiac Arrest: A Randomized Clinical TrialAndrea D Shields, Jacqueline Vidosh, Charles Minard, et al.Molecular Cell|October 1, 2019
Metabolic Diversity in Human Non-Small Cell Lung Cancer CellsPei-Hsuan Chen, Ling Cai, Kenneth Huffman, et al.Journal of Medicinal Chemistry|March 30, 2018
Discovery of a Potent (4 R,5 S)-4-Fluoro-5-methylproline Sulfonamide Transient Receptor Potential Ankyrin 1 Antagonist and Its Methylene Phosphate Prodrug Guided by Molecular ModelingHuifen Chen, Matthew Volgraf, Steven Do, et al.Journal of Medicinal Chemistry|April 4, 2019
Structure- and Ligand-Based Discovery of Chromane Arylsulfonamide Nav1.7 Inhibitors for the Treatment of Chronic PainSteven J McKerrall, Teresa Nguyen, Kwong Wah Lai, et al.RSC Medicinal Chemistry|June 16, 2025
Synthetic chemistry enabling the discovery and development of a series of pyrazoles as HPK1 inhibitorsAnthony J Metrano, Lucas A Morrill, Gayathri Bommakanti, et al.Journal of Medicinal Chemistry|March 22, 2021
Tetrahydrofuran-Based Transient Receptor Potential Ankyrin 1 (TRPA1) Antagonists: Ligand-Based Discovery, Activity in a Rodent Asthma Model, and Mechanism-of-Action via Cryogenic Electron MicroscopyJack A Terrett, Huifen Chen, Daniel G Shore, et al.Journal of Medicinal Chemistry|March 8, 2021
Discovery of Acyl-sulfonamide Nav1.7 Inhibitors GDC-0276 and GDC-0310Brian S Safina, Steven J McKerrall, Shaoyi Sun, et al.Journal of Medicinal Chemistry|March 3, 2024
Discovery of TRPA1 Antagonist GDC-6599: Derisking Preclinical Toxicity and Aldehyde Oxidase Metabolism with a Potential First-in-Class Therapy for Respiratory DiseaseJack A Terrett, Justin Q Ly, Paula Katavolos, et al.Pageof 51