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ACS Medicinal Chemistry Letters|June 6, 2014
Discovery and Hit-to-Lead Optimization of Non-ATP Competitive MK2 (MAPKAPK2) InhibitorsXiaohua Huang, Gerald W Shipps, Cliff C Cheng, et al.Journal of Medicinal Chemistry|January 2, 2010
Application of fragment-based NMR screening, X-ray crystallography, structure-based design, and focused chemical library design to identify novel microM leads for the development of nM BACE-1 (beta-site APP cleaving enzyme 1) inhibitorsYu-Sen Wang, Corey Strickland, Johannes H Voigt, et al.Journal of Medicinal Chemistry|January 2, 2010
Discovery of cyclic acylguanidines as highly potent and selective beta-site amyloid cleaving enzyme (BACE) inhibitors: Part I--inhibitor design and validationZhaoning Zhu, Zhong-Yue Sun, Yuanzan Ye, et al.Nature Communications|January 3, 2026
WRN structural flexibility showcased through fragment-based lead discovery of inhibitorsRachel L Palte, Mihir Mandal, Justyna Sikorska, et al.Journal of Medicinal Chemistry|March 25, 2022
Discovery of MK-1454: A Potent Cyclic Dinucleotide Stimulator of Interferon Genes Agonist for the Treatment of CancerWonsuk Chang, Michael D Altman, Charles A Lesburg, et al.Journal of Medicinal Chemistry|December 8, 2022
Rapid Evolution of a Fragment-like Molecule to Pan-Metallo-Beta-Lactamase Inhibitors: Initial Leads toward Clinical CandidatesMihirbaran Mandal, Li Xiao, Weidong Pan, et al.Science (New York, N.Y.)|August 22, 2020
An orally available non-nucleotide STING agonist with antitumor activityBo-Sheng Pan, Samanthi A Perera, Jennifer A Piesvaux, et al.ACS Medicinal Chemistry Letters|July 14, 2026
Discovery of MK-2118, a Small-Molecule Agonist of STINGTimothy Henderson, Michael D Altman, Alexei V Buevich, et al.British Journal of Sports Medicine|March 3, 2025
Recommendations for use of extracorporeal shockwave therapy in sports medicine: an international modified Delphi studyHye Chang Rhim, Mani Singh, Nicola Maffulli, et al.Pageof 17