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Nature Communications|March 15, 2012
Lipid storage disorders block lysosomal trafficking by inhibiting a TRP channel and lysosomal calcium releaseDongbiao Shen, Xiang Wang, Xinran Li, et al.ACS Infectious Diseases|June 30, 2022
Optimization of Benzoxazinorifamycins to Minimize hPXR Activation for the Treatment of Tuberculosis and HIV CoinfectionShireen R Ashkar, Walajapet Rajeswaran, Pil H Lee, et al.Bioorganic & Medicinal Chemistry Letters|December 8, 2009
Design, synthesis and prostate cancer cell-based studies of analogs of the Rho/MKL1 transcriptional pathway inhibitor, CCG-1423Chris R Evelyn, Jessica L Bell, Jenny G Ryu, et al.Molecular Pharmacology|May 12, 2012
Allosteric modulation of endogenous metabolites as an avenue for drug discoveryDenise Wootten, Emilia E Savage, Celine Valant, et al.Journal of Medicinal Chemistry|January 6, 1995
Tyrosine kinase inhibitors. 4. Structure-activity relationships among N- and 3-substituted 2,2'-dithiobis(1H-indoles) for in vitro inhibition of receptor and nonreceptor protein tyrosine kinasesB D Palmer, G W Rewcastle, A M Thompson, et al.Plos One|April 4, 2014
A novel humanized GLP-1 receptor model enables both affinity purification and Cre-LoxP deletion of the receptorLucy S Jun, Aaron D Showalter, Nosher Ali, et al.Bioorganic & Medicinal Chemistry Letters|September 11, 2004
Synthesis and structural-activity relationships of 3-hydroxyquinazoline-2,4-dione antibacterial agentsTuan P Tran, Edmund L Ellsworth, Michael A Stier, et al.Antimicrobial Agents and Chemotherapy|May 4, 2016
Anti-infective Activity of 2-Cyano-3-Acrylamide Inhibitors with Improved Drug-Like Properties against Two Intracellular PathogensKarla D Passalacqua, Marie-Eve Charbonneau, Nicholas J Donato, et al.Journal of Medicinal Chemistry|May 5, 2018
Design, Synthesis, and Biological Evaluation of 4-Quinoline Carboxylic Acids as Inhibitors of Dihydroorotate DehydrogenaseJoseph T Madak, Christine R Cuthbertson, Yoshinari Miyata, et al.Journal of Medicinal Chemistry|February 16, 1996
Tyrosine kinase inhibitors. 9. Synthesis and evaluation of fused tricyclic quinazoline analogues as ATP site inhibitors of the tyrosine kinase activity of the epidermal growth factor receptorG W Rewcastle, B D Palmer, A J Bridges, et al.Pageof 22