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Eclinicalmedicine|October 28, 2025
Safety, pharmacokinetic, pharmacodynamic, and efficacy properties of orally administered APG-2449 in patients with advanced ALK + and ROS1 + non-small-cell lung cancer: a multicentre, open-label, single-arm phase 1 trialYuxiang Ma, Zhengbo Song, Jianhua Chen, et al.Clinical Cancer Research : an Official Journal of the American Association for Cancer Research|September 1, 2022
Lisaftoclax (APG-2575) Is a Novel BCL-2 Inhibitor with Robust Antitumor Activity in Preclinical Models of Hematologic MalignancyJing Deng, Aneel Paulus, Douglas D Fang, et al.Cancer Research|October 5, 2006
Targeting the lymphotoxin-beta receptor with agonist antibodies as a potential cancer therapyMatvey Lukashev, Doreen LePage, Cheryl Wilson, et al.Med (New York, N.Y.)|October 18, 2025
Safety, tolerability, and pharmacokinetics of lisaftoclax (APG-2575)-based therapy in patients with chronic lymphocytic leukemia: Phase 1b/2 studyMatthew S Davids, Asher Chanan-Khan, Sikander Ailawadhi, et al.Pageof 12