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Organic & Biomolecular Chemistry|December 22, 2018
Synthesis and biophysical characterization of oligonucleotides modified with O2'-alkylated RNA monomers featuring substituted pyrene moietiesSaswata Karmakar, Tyler Horrocks, Bradley C Gibbons, et al.
Chembiochem : a European Journal of Chemical Biology|September 17, 2013
Invaders: Recognition of Double-Stranded DNA by Using Duplexes Modified with Interstrand Zippers of 2'-O-(Pyren-1-yl)methyl-ribonucleotidesBradley A Didion, Saswata Karmakar, Dale C Guenther, et al.
The Journal of Organic Chemistry|May 7, 2014
C5-alkynyl-functionalized α-L-LNA: synthesis, thermal denaturation experiments and enzymatic stabilityPawan Kumar, Bharat Baral, Brooke A Anderson, et al.
Chemical Communications (Cambridge, England)|June 8, 2010
Pyrene-functionalized triazole-linked 2'-deoxyuridines-probes for discrimination of single nucleotide polymorphisms (SNPs)Michael E Østergaard, Dale C Guenther, Pawan Kumar, et al.
Chemical Science|August 5, 2015
Invader probes: Harnessing the energy of intercalation to facilitate recognition of chromosomal DNA for diagnostic applicationsDale C Guenther, Grace H Anderson, Saswata Karmakar, et al.
The Journal of Organic Chemistry|May 15, 2014
Synthesis and biophysical properties of C5-functionalized LNA (locked nucleic acid)Pawan Kumar, Michael E Østergaard, Bharat Baral, et al.
Chemistry (Weinheim an Der Bergstrasse, Germany)|February 18, 2011
C5-functionalized DNA, LNA, and α-L-LNA: positional control of polarity-sensitive fluorophores leads to improved SNP-typingMichael E Østergaard, Pawan Kumar, Bharat Baral, et al.
Journal of the American Chemical Society|October 7, 2024
Single-Stranded Hairpin Loop RNAs (loopmeRNAs) Potently Induce Gene Silencing through the RNA Interference PathwayKrishna C Aluri, Dhrubajyoti Datta, Scott Waldron, et al.
Nucleic Acids Research|August 15, 2018
Structural basis for the synergy of 4'- and 2'-modifications on siRNA nuclease resistance, thermal stability and RNAi activityJoel M Harp, Dale C Guenther, Anna Bisbe, et al.
Nucleic Acids Research|March 15, 2020
Chimeric siRNAs with chemically modified pentofuranose and hexopyranose nucleotides: altritol-nucleotide (ANA) containing GalNAc-siRNA conjugates: in vitro and in vivo RNAi activity and resistance to 5'-exonucleasePawan Kumar, Rohan Degaonkar, Dale C Guenther, et al.
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