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The Journal of Biological Chemistry|January 24, 2003
Catalytic mechanism of Escherichia coli isopentenyl diphosphate isomerase involves Cys-67, Glu-116, and Tyr-104 as suggested by crystal structures of complexes with transition state analogues and irreversible inhibitorsJ Wouters, Y Oudjama, Sam J Barkley, et al.
The Journal of Organic Chemistry|June 16, 2010
Enantioselective inhibition of squalene synthase by aziridine analogues of presqualene diphosphateAli Koohang, Jessica L Bailey, Robert M Coates, et al.
The Journal of Organic Chemistry|September 4, 2014
Synthesis of methylerythritol phosphate analogues and their evaluation as alternate substrates for IspDF and IspE from Agrobacterium tumefaciensSergiy G Krasutsky, Marek Urbansky, Chad E Davis, et al.
Chembiochem : a European Journal of Chemical Biology|September 2, 2017
Further Insight into Crystal Structures of Escherichia coli IspH/LytB in Complex with Two Potent Inhibitors of the MEP Pathway: A Starting Point for Rational Design of New AntimicrobialsFranck Borel, Elodie Barbier, Sergiy Krasutsky, et al.
The Journal of Organic Chemistry|March 4, 2015
Synthesis and enzymatic studies of bisubstrate analogues for farnesyl diphosphate synthaseGurusankar Ramamoorthy, Mark L Pugh, Bo-Xue Tian, et al.
Plos Computational Biology|October 10, 2014
Predicting the functions and specificity of triterpenoid synthases: a mechanism-based multi-intermediate docking approachBo-Xue Tian, Frank H Wallrapp, Gemma L Holiday, et al.
ACS Central Science|August 11, 2015
Biosynthesis of Squalene from Farnesyl Diphosphate in Bacteria: Three Steps Catalyzed by Three EnzymesJian-Jung Pan, Jose O Solbiati, Gurusankar Ramamoorthy, et al.
Proceedings of the National Academy of Sciences of the United States of America|April 23, 2015
Computational-guided discovery and characterization of a sesquiterpene synthase from Streptomyces clavuligerusJeng-Yeong Chow, Bo-Xue Tian, Gurusankar Ramamoorthy, et al.
Chembiochem : a European Journal of Chemical Biology|June 10, 2014
Determination of kinetics and the crystal structure of a novel type 2 isopentenyl diphosphate: dimethylallyl diphosphate isomerase from Streptococcus pneumoniaeJerome de Ruyck, Matthew W Janczak, Syam Sundar Neti, et al.
Bioorganic & Medicinal Chemistry|November 28, 2012
Novel route to chaetomellic acid A and analogues: serendipitous discovery of a more competent FTase inhibitorFranco Bellesia, Seoung-ryoung Choi, Fulvia Felluga, et al.
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