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Cancer Discovery
|
February 26, 2021
Mobocertinib (TAK-788): A Targeted Inhibitor of <i>EGFR</i> Exon 20 Insertion Mutants in Non-Small Cell Lung Cancer
Francois Gonzalvez, Sylvie Vincent, Theresa E Baker, et al.
Bioorganic & Medicinal Chemistry Letters
|
August 28, 2003
Bone-targeted pyrido[2,3-d]pyrimidin-7-ones: potent inhibitors of Src tyrosine kinase as novel antiresorptive agents
Chi B Vu, George P Luke, Noriyuki Kawahata, et al.
Cancer Cell
|
November 3, 2009
AP24534, a pan-BCR-ABL inhibitor for chronic myeloid leukemia, potently inhibits the T315I mutant and overcomes mutation-based resistance
Thomas O'Hare, William C Shakespeare, Xiaotian Zhu, et al.
Nature Communications
|
July 24, 2024
Pannexin-1 channel inhibition alleviates opioid withdrawal in rodents by modulating locus coeruleus to spinal cord circuitry
Charlie H T Kwok, Erika K Harding, Nicole E Burma, et al.
Bioorganic & Medicinal Chemistry Letters
|
May 13, 2011
Discovery of 5-(arenethynyl) hetero-monocyclic derivatives as potent inhibitors of BCR-ABL including the T315I gatekeeper mutant
Mathew Thomas, Wei-Sheng Huang, David Wen, et al.
Journal of Medicinal Chemistry
|
May 5, 2016
Discovery of Brigatinib (AP26113), a Phosphine Oxide-Containing, Potent, Orally Active Inhibitor of Anaplastic Lymphoma Kinase
Wei-Sheng Huang, Shuangying Liu, Dong Zou, et al.
Journal of Medicinal Chemistry
|
June 2, 2010
Discovery of 3-[2-(imidazo[1,2-b]pyridazin-3-yl)ethynyl]-4-methyl-N-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}benzamide (AP24534), a potent, orally active pan-inhibitor of breakpoint cluster region-abelson (BCR-ABL) kinase including the T315I gatekeeper mutant
Wei-Sheng Huang, Chester A Metcalf, Raji Sundaramoorthi, et al.
Bioorganic & Medicinal Chemistry Letters
|
November 24, 2022
Discovery of mobocertinib, a potent, oral inhibitor of EGFR exon 20 insertion mutations in non-small cell lung cancer
Wei-Sheng Huang, Feng Li, Yongjin Gong, et al.
Cancers
|
July 2, 2021
Dissection of <i>PIK3CA</i> Aberration for Cervical Adenocarcinoma Outcomes
Tony K H Chung, Graeme Doran, Tak-Hong Cheung, et al.
Page
of 48
Search research articles
Search
Showing results (471-480 of 479) with videos related to
Sort By:
Page
of 48
You have reached the last page of results.
This site can display upto 479 results.
Cancer Discovery
|
February 26, 2021
Mobocertinib (TAK-788): A Targeted Inhibitor of <i>EGFR</i> Exon 20 Insertion Mutants in Non-Small Cell Lung Cancer
Francois Gonzalvez, Sylvie Vincent, Theresa E Baker, et al.
Bioorganic & Medicinal Chemistry Letters
|
August 28, 2003
Bone-targeted pyrido[2,3-d]pyrimidin-7-ones: potent inhibitors of Src tyrosine kinase as novel antiresorptive agents
Chi B Vu, George P Luke, Noriyuki Kawahata, et al.
Cancer Cell
|
November 3, 2009
AP24534, a pan-BCR-ABL inhibitor for chronic myeloid leukemia, potently inhibits the T315I mutant and overcomes mutation-based resistance
Thomas O'Hare, William C Shakespeare, Xiaotian Zhu, et al.
Nature Communications
|
July 24, 2024
Pannexin-1 channel inhibition alleviates opioid withdrawal in rodents by modulating locus coeruleus to spinal cord circuitry
Charlie H T Kwok, Erika K Harding, Nicole E Burma, et al.
Bioorganic & Medicinal Chemistry Letters
|
May 13, 2011
Discovery of 5-(arenethynyl) hetero-monocyclic derivatives as potent inhibitors of BCR-ABL including the T315I gatekeeper mutant
Mathew Thomas, Wei-Sheng Huang, David Wen, et al.
Journal of Medicinal Chemistry
|
May 5, 2016
Discovery of Brigatinib (AP26113), a Phosphine Oxide-Containing, Potent, Orally Active Inhibitor of Anaplastic Lymphoma Kinase
Wei-Sheng Huang, Shuangying Liu, Dong Zou, et al.
Journal of Medicinal Chemistry
|
June 2, 2010
Discovery of 3-[2-(imidazo[1,2-b]pyridazin-3-yl)ethynyl]-4-methyl-N-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}benzamide (AP24534), a potent, orally active pan-inhibitor of breakpoint cluster region-abelson (BCR-ABL) kinase including the T315I gatekeeper mutant
Wei-Sheng Huang, Chester A Metcalf, Raji Sundaramoorthi, et al.
Bioorganic & Medicinal Chemistry Letters
|
November 24, 2022
Discovery of mobocertinib, a potent, oral inhibitor of EGFR exon 20 insertion mutations in non-small cell lung cancer
Wei-Sheng Huang, Feng Li, Yongjin Gong, et al.
Cancers
|
July 2, 2021
Dissection of <i>PIK3CA</i> Aberration for Cervical Adenocarcinoma Outcomes
Tony K H Chung, Graeme Doran, Tak-Hong Cheung, et al.
Page
of 48