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Nucleic Acids Research|February 17, 2024
Unfilled gaps by polβ lead to aberrant ligation by LIG1 at the downstream steps of base excision repair pathwayMitchell Gulkis, Ernesto Martinez, Danah Almohdar, et al.
The Journal of Biological Chemistry|March 24, 2024
Structures of LIG1 provide a mechanistic basis for understanding a lack of sugar discrimination against a ribonucleotide at the 3'-end of nick DNAKanal Elamparithi Balu, Mitchell Gulkis, Danah Almohdar, et al.
Journal of Molecular Biology|December 22, 2023
Impact of polβ/XRCC1 Interaction Variants on the Efficiency of Nick Sealing by DNA Ligase IIIα in the Base Excision Repair PathwayDanah Almohdar, Mitchell Gulkis, Abigail Ortiz, et al.
The Journal of Biological Chemistry|August 19, 2024
Structures of LIG1 uncover the mechanism of sugar discrimination against 5'-RNA-DNA junctions during ribonucleotide excision repairKanal Elamparithi Balu, Qun Tang, Danah Almohdar, et al.
Biorxiv : the Preprint Server for Biology|May 20, 2024
Structural and biochemical characterization of LIG1 during mutagenic nick sealing of oxidatively damaged ends at the final step of DNA repairKanal Elamparithi Balu, Danah Almohdar, Jacob Ratcliffe, et al.
Mutagenesis|May 13, 2024
Impact of DNA ligase inhibition on the nick sealing of polβ nucleotide insertion products at the downstream steps of base excision repair pathwayDanah Almohdar, Pradnya Kamble, Chandrakala Basavannacharya, et al.
The Journal of Biological Chemistry|May 8, 2024
Impact of DNA ligase 1 and IIIα interactions with APE1 and polβ on the efficiency of base excision repair pathway at the downstream stepsDanah Almohdar, David Murcia, Qun Tang, et al.
Nucleic Acids Research|October 15, 2024
Probing the mechanism of nick searching by LIG1 at the single-molecule levelSurajit Chatterjee, Loïc Chaubet, Aafke van den Berg, et al.
Nucleic Acids Research|December 10, 2025
Processing of DNA single-strand breaks with oxidatively damaged ends by LIG1Kanal E Balu, Danah Almohdar, Camden Lerner, et al.
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