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Chemmedchem|July 21, 2016
Hedgehog Proteins Consume Steroidal CYP17A1 Antagonists: Potential Therapeutic Significance in Advanced Prostate CancerBrandon M Bordeau, Daniel A Ciulla, Brian P CallahanJournal of the American Chemical Society|September 21, 2017
Chemical Bypass of General Base Catalysis in Hedgehog Protein Cholesterolysis Using a Hyper-Nucleophilic SubstrateDaniel A Ciulla, Michael T Jorgensen, José-Luis Giner, et al.Biochemistry|September 15, 2020
Specificity Distorted: Chemical Induction of Biological ParacatalysisBrian P Callahan, Daniel A Ciulla, Andrew G Wagner, et al.Methods in Enzymology|May 28, 2023
Paracatalytic induction: Subverting specificity in hedgehog protein autoprocessing with small moleculesDaniel A Ciulla, Zihan Xu, John L Pezzullo, et al.Bioconjugate Chemistry|October 11, 2019
Protein-Nucleic Acid Conjugation with Sterol Linkers Using Hedgehog AutoprocessingXiaoyu Zhang, Zihan Xu, Dina S Moumin, et al.The Journal of Biological Chemistry|November 18, 2022
A cell-based bioluminescence reporter assay of human Sonic Hedgehog protein autoprocessing to identify inhibitors and activatorsDaniel A Ciulla, Patricia Dranchak, John L Pezzullo, et al.Nature Communications|May 9, 2025
A general assay platform to study protein pharmacology using ligand-dependent structural dynamicsDaniel A Ciulla, Patricia K Dranchak, Mahesh Aitha, et al.Chemical Communications (Cambridge, England)|January 24, 2019
Sterol A-ring plasticity in hedgehog protein cholesterolysis supports a primitive substrate selectivity mechanismDaniel A Ciulla, Andrew G Wagner, Xinyue Liu, et al.Journal of the American Chemical Society|November 5, 2019
General Base Swap Preserves Activity and Expands Substrate Tolerance in Hedgehog AutoprocessingJing Zhao, Daniel A Ciulla, Jian Xie, et al.Pageof 1