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Current Topics in Medicinal Chemistry
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April 18, 2017
Calculating Water Thermodynamics in the Binding Site of Proteins - Applications of WaterMap to Drug Discovery
Daniel Cappel, Woody Sherman, Thijs Beuming
Journal of Chemical Information and Modeling
|
January 28, 2020
Impact of Different Automated Binding Pose Generation Approaches on Relative Binding Free Energy Simulations
Daniel Cappel, Steven Jerome, Gerhard Hessler, et al.
Journal of Chemical Information and Modeling
|
June 25, 2021
Performance of Relative Binding Free Energy Calculations on an Automatically Generated Dataset of Halogen-Deshalogen Matched Molecular Pairs
Daniel Cappel, Jean-Christophe Mozziconacci, Tatjana Braun, et al.
Journal of Computer-Aided Molecular Design
|
November 20, 2014
Exploring conformational search protocols for ligand-based virtual screening and 3-D QSAR modeling
Daniel Cappel, Steven L Dixon, Woody Sherman, et al.
Journal of Chemical Information and Modeling
|
September 16, 2011
Probing the dynamic nature of water molecules and their influences on ligand binding in a model binding site
Daniel Cappel, Rickard Wahlström, Ruth Brenk, et al.
Plos One
|
March 2, 2013
Molecular dynamics reveal binding mode of glutathionylspermidine by trypanothione synthetase
Oliver Koch, Daniel Cappel, Monika Nocker, et al.
Journal of Chemical Information and Modeling
|
December 28, 2016
Relative Binding Free Energy Calculations Applied to Protein Homology Models
Daniel Cappel, Michelle Lynn Hall, Eelke B Lenselink, et al.
Journal of Medicinal Chemistry
|
July 10, 2014
Optimization of potent DFG-in inhibitors of platelet derived growth factor receptorβ (PDGF-Rβ) guided by water thermodynamics
Rebecca Horbert, Boris Pinchuk, Eugen Johannes, et al.
Journal of Chemical Information and Modeling
|
October 13, 2015
Accurate Binding Free Energy Predictions in Fragment Optimization
Thomas B Steinbrecher, Markus Dahlgren, Daniel Cappel, et al.
Chemmedchem
|
November 1, 2018
The Role of Bridging Water and Hydrogen Bonding as Key Determinants of Noncovalent Protein-Carbohydrate Recognition
Anatoly M Ruvinsky, Ishita Aloni, Daniel Cappel, et al.
Page
of 2
Search research articles
Search
Showing results (1-10 of 13) with videos related to
Sort By:
Page
of 2
Current Topics in Medicinal Chemistry
|
April 18, 2017
Calculating Water Thermodynamics in the Binding Site of Proteins - Applications of WaterMap to Drug Discovery
Daniel Cappel, Woody Sherman, Thijs Beuming
Journal of Chemical Information and Modeling
|
January 28, 2020
Impact of Different Automated Binding Pose Generation Approaches on Relative Binding Free Energy Simulations
Daniel Cappel, Steven Jerome, Gerhard Hessler, et al.
Journal of Chemical Information and Modeling
|
June 25, 2021
Performance of Relative Binding Free Energy Calculations on an Automatically Generated Dataset of Halogen-Deshalogen Matched Molecular Pairs
Daniel Cappel, Jean-Christophe Mozziconacci, Tatjana Braun, et al.
Journal of Computer-Aided Molecular Design
|
November 20, 2014
Exploring conformational search protocols for ligand-based virtual screening and 3-D QSAR modeling
Daniel Cappel, Steven L Dixon, Woody Sherman, et al.
Journal of Chemical Information and Modeling
|
September 16, 2011
Probing the dynamic nature of water molecules and their influences on ligand binding in a model binding site
Daniel Cappel, Rickard Wahlström, Ruth Brenk, et al.
Plos One
|
March 2, 2013
Molecular dynamics reveal binding mode of glutathionylspermidine by trypanothione synthetase
Oliver Koch, Daniel Cappel, Monika Nocker, et al.
Journal of Chemical Information and Modeling
|
December 28, 2016
Relative Binding Free Energy Calculations Applied to Protein Homology Models
Daniel Cappel, Michelle Lynn Hall, Eelke B Lenselink, et al.
Journal of Medicinal Chemistry
|
July 10, 2014
Optimization of potent DFG-in inhibitors of platelet derived growth factor receptorβ (PDGF-Rβ) guided by water thermodynamics
Rebecca Horbert, Boris Pinchuk, Eugen Johannes, et al.
Journal of Chemical Information and Modeling
|
October 13, 2015
Accurate Binding Free Energy Predictions in Fragment Optimization
Thomas B Steinbrecher, Markus Dahlgren, Daniel Cappel, et al.
Chemmedchem
|
November 1, 2018
The Role of Bridging Water and Hydrogen Bonding as Key Determinants of Noncovalent Protein-Carbohydrate Recognition
Anatoly M Ruvinsky, Ishita Aloni, Daniel Cappel, et al.
Page
of 2