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Genes & Development|August 3, 2006
In vivo commitment to yeast cotranscriptional splicing is sensitive to transcription elongation mutantsScott A Lacadie, Daniel F Tardiff, Sebastian Kadener, et al.
The Journal of Biological Chemistry|December 8, 2011
Different 8-hydroxyquinolines protect models of TDP-43 protein, α-synuclein, and polyglutamine proteotoxicity through distinct mechanismsDaniel F Tardiff, Michelle L Tucci, Kim A Caldwell, et al.
Proceedings of the National Academy of Sciences of the United States of America|March 5, 2014
Clioquinol promotes the degradation of metal-dependent amyloid-β (Aβ) oligomers to restore endocytosis and ameliorate Aβ toxicityKent E S Matlack, Daniel F Tardiff, Priyanka Narayan, et al.
Molecular Neurobiology|January 21, 2022
Non-clinical Pharmacology of YTX-7739: a Clinical Stage Stearoyl-CoA Desaturase Inhibitor Being Developed for Parkinson's DiseaseDaniel F Tardiff, Matthew Lucas, Iwona Wrona, et al.
ACS Chemical Neuroscience|June 20, 2017
Dihydropyrimidine-Thiones and Clioquinol Synergize To Target β-Amyloid Cellular Pathologies through a Metal-Dependent MechanismDaniel F Tardiff, Lauren E Brown, Xiaohui Yan, et al.
Plos Biology|May 5, 2011
A yeast model of FUS/TLS-dependent cytotoxicityShulin Ju, Daniel F Tardiff, Haesun Han, et al.
Science Translational Medicine|January 18, 2023
Targeting de novo lipid synthesis induces lipotoxicity and impairs DNA damage repair in glioblastoma mouse modelsKatharina M Eyme, Alessandro Sammarco, Roshani Jha, et al.
Science (New York, N.Y.)|October 26, 2013
Yeast reveal a "druggable" Rsp5/Nedd4 network that ameliorates α-synuclein toxicity in neuronsDaniel F Tardiff, Nathan T Jui, Vikram Khurana, et al.
Neurotherapeutics : the Journal of the American Society for Experimental Neurotherapeutics|April 21, 2022
A Brain-Penetrant Stearoyl-CoA Desaturase Inhibitor Reverses α-Synuclein ToxicitySilke Nuber, Chee Yeun Chung, Daniel F Tardiff, et al.
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