Showing results (1-10 of 8) with videos related to

Sort By:
Pageof 1
Heart Rhythm|May 14, 2020
Phenotype-guided whole genome analysis in a patient with genetically elusive long QT syndrome yields a novel TRDN-encoded triadin pathogenetic substrate for triadin knockout syndrome and reveals a novel primate-specific cardiac TRDN transcriptDaniel J Clemens, David J Tester, Isabelle Marty, et al.
Stem Cells and Development|November 21, 2019
Human Induced Pluripotent Stem Cell-Derived Non-Cardiomyocytes Modulate Cardiac Electrophysiological Maturation Through Connexin 43-Mediated Cell-Cell InteractionsSherri M Biendarra-Tiegs, Daniel J Clemens, Frank J Secreto, et al.
Heart Rhythm|December 4, 2017
Using the genome aggregation database, computational pathogenicity prediction tools, and patch clamp heterologous expression studies to demote previously published long QT syndrome type 1 mutations from pathogenic to benignDaniel J Clemens, Anne R Lentino, Jamie D Kapplinger, et al.
Heart Rhythm|September 8, 2019
Utilization of the genome aggregation database, in silico tools, and heterologous expression patch-clamp studies to identify and demote previously published type 2 long QT syndrome: Causative variants from pathogenic to likely benignConnor L Mattivi, Dan Ye, David J Tester, et al.
Circulation. Genomic and Precision Medicine|March 14, 2020
Triadin Knockout Syndrome Is Absent in a Multi-Center Molecular Autopsy Cohort of Sudden Infant Death Syndrome and Sudden Unexplained Death in the Young and Is Extremely Rare in the General PopulationDaniel J Clemens, Belinda Gray, Richard D Bagnall, et al.
Stem Cell Reports|May 10, 2023
Cellular and electrophysiological characterization of triadin knockout syndrome using induced pluripotent stem cell-derived cardiomyocytesDaniel J Clemens, Dan Ye, Lili Wang, et al.
Plos One|March 8, 2023
SARS-CoV-2 spike protein-mediated cardiomyocyte fusion may contribute to increased arrhythmic risk in COVID-19Daniel J Clemens, Dan Ye, Wei Zhou, et al.
Circulation. Genomic and Precision Medicine|January 17, 2019
International Triadin Knockout Syndrome RegistryDaniel J Clemens, David J Tester, John R Giudicessi, et al.
Pageof 1