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ACS Medicinal Chemistry Letters
|
January 8, 2026
Dual Nurr1/RXR agonism of valerenic acid and synthetic mimetics enables dimer-selective Nurr1 modulation
Katharina Scholz, Úrsula López-García, Romy Busch, et al.
Nature Communications
|
April 11, 2026
Structural optimization of drug molecules with incrementally trained language models
Tim Hörmann, Domenic Mayer, Max Lewandowski, et al.
Biochemical Pharmacology
|
May 27, 2019
A dual farnesoid X receptor/soluble epoxide hydrolase modulator treats non-alcoholic steatohepatitis in mice
Md Abdul Hye Khan, Jurema Schmidt, Anna Stavniichuk, et al.
Journal of Medicinal Chemistry
|
October 23, 2025
Scaffold Fusion and SAR Transfer with a Chemical Language Model Generates Novel Liver X Receptor Modulators
Nils Christiaan Bandomir, Tim Hörmann, Annette Kärcher, et al.
Future Medicinal Chemistry
|
January 30, 2016
SAR studies on FXR modulators led to the discovery of the first combined FXR antagonistic/TGR5 agonistic compound
Christina Lamers, Daniel Merk, Matthias Gabler, et al.
International Journal of Molecular Sciences
|
September 9, 2022
Activity Screening of Fatty Acid Mimetic Drugs Identified Nuclear Receptor Agonists
Moritz Helmstädter, Simone Schierle, Laura Isigkeit, et al.
Frontiers in Immunology
|
January 18, 2024
Dual soluble epoxide hydrolase inhibitor - farnesoid X receptor agonist interventional treatment attenuates renal inflammation and fibrosis
Md Abdul Hye Khan, Benjamin Nolan, Anna Stavniichuk, et al.
Communications Chemistry
|
January 27, 2023
The orphan nuclear receptor Nurr1 is responsive to non-steroidal anti-inflammatory drugs
Sabine Willems, Whitney Kilu, Xiaomin Ni, et al.
Journal of Medicinal Chemistry
|
July 21, 2020
Design and Structural Optimization of Dual FXR/PPARδ Activators
Simone Schierle, Sebastian Neumann, Pascal Heitel, et al.
International Journal of Molecular Sciences
|
November 14, 2020
Comprehensive Set of Tertiary Complex Structures and Palmitic Acid Binding Provide Molecular Insights into Ligand Design for RXR Isoforms
Apirat Chaikuad, Julius Pollinger, Michael Rühl, et al.
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of 17
Search research articles
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Showing results (61-70 of 165) with videos related to
Sort By:
Page
of 17
ACS Medicinal Chemistry Letters
|
January 8, 2026
Dual Nurr1/RXR agonism of valerenic acid and synthetic mimetics enables dimer-selective Nurr1 modulation
Katharina Scholz, Úrsula López-García, Romy Busch, et al.
Nature Communications
|
April 11, 2026
Structural optimization of drug molecules with incrementally trained language models
Tim Hörmann, Domenic Mayer, Max Lewandowski, et al.
Biochemical Pharmacology
|
May 27, 2019
A dual farnesoid X receptor/soluble epoxide hydrolase modulator treats non-alcoholic steatohepatitis in mice
Md Abdul Hye Khan, Jurema Schmidt, Anna Stavniichuk, et al.
Journal of Medicinal Chemistry
|
October 23, 2025
Scaffold Fusion and SAR Transfer with a Chemical Language Model Generates Novel Liver X Receptor Modulators
Nils Christiaan Bandomir, Tim Hörmann, Annette Kärcher, et al.
Future Medicinal Chemistry
|
January 30, 2016
SAR studies on FXR modulators led to the discovery of the first combined FXR antagonistic/TGR5 agonistic compound
Christina Lamers, Daniel Merk, Matthias Gabler, et al.
International Journal of Molecular Sciences
|
September 9, 2022
Activity Screening of Fatty Acid Mimetic Drugs Identified Nuclear Receptor Agonists
Moritz Helmstädter, Simone Schierle, Laura Isigkeit, et al.
Frontiers in Immunology
|
January 18, 2024
Dual soluble epoxide hydrolase inhibitor - farnesoid X receptor agonist interventional treatment attenuates renal inflammation and fibrosis
Md Abdul Hye Khan, Benjamin Nolan, Anna Stavniichuk, et al.
Communications Chemistry
|
January 27, 2023
The orphan nuclear receptor Nurr1 is responsive to non-steroidal anti-inflammatory drugs
Sabine Willems, Whitney Kilu, Xiaomin Ni, et al.
Journal of Medicinal Chemistry
|
July 21, 2020
Design and Structural Optimization of Dual FXR/PPARδ Activators
Simone Schierle, Sebastian Neumann, Pascal Heitel, et al.
International Journal of Molecular Sciences
|
November 14, 2020
Comprehensive Set of Tertiary Complex Structures and Palmitic Acid Binding Provide Molecular Insights into Ligand Design for RXR Isoforms
Apirat Chaikuad, Julius Pollinger, Michael Rühl, et al.
Page
of 17