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ACS Medicinal Chemistry Letters
|
February 19, 2021
A New FXR Ligand Chemotype with Agonist/Antagonist Switch
Moritz Helmstädter, Jan Vietor, Jana Sommer, et al.
ACS Medicinal Chemistry Letters
|
February 21, 2019
Computer-Assisted Discovery and Structural Optimization of a Novel Retinoid X Receptor Agonist Chemotype
Pascal Heitel, Leonie Gellrich, Lena Kalinowsky, et al.
Communications Chemistry
|
May 21, 2025
Structural and mechanistic profiling of Nurr1 modulation by vidofludimus enables structure-guided ligand design
Úrsula López-García, Jan Vietor, Julian A Marschner, et al.
Journal of Medicinal Chemistry
|
September 26, 2014
Extending the structure-activity relationship of anthranilic acid derivatives as farnesoid X receptor modulators: development of a highly potent partial farnesoid X receptor agonist
Daniel Merk, Christina Lamers, Khalil Ahmad, et al.
Journal of Medicinal Chemistry
|
June 24, 2021
Second-Generation Dual FXR/sEH Modulators with Optimized Pharmacokinetics
Moritz Helmstädter, Astrid Kaiser, Steffen Brunst, et al.
Journal of Medicinal Chemistry
|
January 28, 2026
Systematic Optimization of Fragment TLX Ligands toward Agonism and Inverse Agonism
Emily C Hank, Loris Knümann, Úrsula López-García, et al.
Journal of Medicinal Chemistry
|
January 26, 2026
Structural Tuning of Vidofludimus for High-Efficacy NR4A Agonism
Jan Vietor, Romy Busch, Úrsula López-García, et al.
Journal of Medicinal Chemistry
|
November 9, 2018
Structure-Based Approach toward Identification of Inhibitory Fragments for Eleven-Nineteen-Leukemia Protein (ENL)
David Heidenreich, Moses Moustakim, Jurema Schmidt, et al.
Journal of Medicinal Chemistry
|
September 18, 2025
Development of Potent and Selective Dual PPARδ/sEH Modulators from an AI-Designed Scaffold
Xiu Ge, Till Kasch, Max Lewandowski, et al.
Scientific Reports
|
September 12, 2018
Urate transporter inhibitor lesinurad is a selective peroxisome proliferator-activated receptor gamma modulator (sPPARγM) in vitro
Pascal Heitel, Leonie Gellrich, Jan Heering, et al.
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of 17
Search research articles
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Showing results (81-90 of 165) with videos related to
Sort By:
Page
of 17
ACS Medicinal Chemistry Letters
|
February 19, 2021
A New FXR Ligand Chemotype with Agonist/Antagonist Switch
Moritz Helmstädter, Jan Vietor, Jana Sommer, et al.
ACS Medicinal Chemistry Letters
|
February 21, 2019
Computer-Assisted Discovery and Structural Optimization of a Novel Retinoid X Receptor Agonist Chemotype
Pascal Heitel, Leonie Gellrich, Lena Kalinowsky, et al.
Communications Chemistry
|
May 21, 2025
Structural and mechanistic profiling of Nurr1 modulation by vidofludimus enables structure-guided ligand design
Úrsula López-García, Jan Vietor, Julian A Marschner, et al.
Journal of Medicinal Chemistry
|
September 26, 2014
Extending the structure-activity relationship of anthranilic acid derivatives as farnesoid X receptor modulators: development of a highly potent partial farnesoid X receptor agonist
Daniel Merk, Christina Lamers, Khalil Ahmad, et al.
Journal of Medicinal Chemistry
|
June 24, 2021
Second-Generation Dual FXR/sEH Modulators with Optimized Pharmacokinetics
Moritz Helmstädter, Astrid Kaiser, Steffen Brunst, et al.
Journal of Medicinal Chemistry
|
January 28, 2026
Systematic Optimization of Fragment TLX Ligands toward Agonism and Inverse Agonism
Emily C Hank, Loris Knümann, Úrsula López-García, et al.
Journal of Medicinal Chemistry
|
January 26, 2026
Structural Tuning of Vidofludimus for High-Efficacy NR4A Agonism
Jan Vietor, Romy Busch, Úrsula López-García, et al.
Journal of Medicinal Chemistry
|
November 9, 2018
Structure-Based Approach toward Identification of Inhibitory Fragments for Eleven-Nineteen-Leukemia Protein (ENL)
David Heidenreich, Moses Moustakim, Jurema Schmidt, et al.
Journal of Medicinal Chemistry
|
September 18, 2025
Development of Potent and Selective Dual PPARδ/sEH Modulators from an AI-Designed Scaffold
Xiu Ge, Till Kasch, Max Lewandowski, et al.
Scientific Reports
|
September 12, 2018
Urate transporter inhibitor lesinurad is a selective peroxisome proliferator-activated receptor gamma modulator (sPPARγM) in vitro
Pascal Heitel, Leonie Gellrich, Jan Heering, et al.
Page
of 17