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Nature Communications|May 12, 2021
The ubiquitylation of IL-1β limits its cleavage by caspase-1 and targets it for proteasomal degradationSwarna L Vijayaraj, Rebecca Feltham, Maryam Rashidi, et al.
Neurochemical Research|December 8, 2009
Hemorphins act as homeostatic agents in response to endotoxin-induced stressNina Barkhudaryan, Hermine Zakaryan, Flora Sarukhanyan, et al.
Journal of Leukocyte Biology|December 28, 2018
Stressing out the mitochondria: Mechanistic insights into NLRP3 inflammasome activationMonica Yabal, Dale J Calleja, Daniel S Simpson, et al.
The Journal of Biological Chemistry|September 12, 2008
Structures of the cIAP2 RING domain reveal conformational changes associated with ubiquitin-conjugating enzyme (E2) recruitmentPeter D Mace, Katrin Linke, Rebecca Feltham, et al.
Cell Chemical Biology|August 3, 2026
The BAX/BAK apoptotic checkpoint polices entry to therapy-induced senescenceAislinn Gallagher Aldave, Vaishnavi Venugopalan, Gokhan Gunay, et al.
The Journal of Biological Chemistry|April 2, 2010
Tumor necrosis factor (TNF) signaling, but not TWEAK (TNF-like weak inducer of apoptosis)-triggered cIAP1 (cellular inhibitor of apoptosis protein 1) degradation, requires cIAP1 RING dimerization and E2 bindingRebecca Feltham, Maryline Moulin, James E Vince, et al.
The EMBO Journal|February 14, 2012
IAPs limit activation of RIP kinases by TNF receptor 1 during developmentMaryline Moulin, Holly Anderton, Anne K Voss, et al.
The Journal of Biological Chemistry|March 12, 2011
Smac mimetics activate the E3 ligase activity of cIAP1 protein by promoting RING domain dimerizationRebecca Feltham, Bodhi Bettjeman, Rhesa Budhidarmo, et al.
Nature Communications|June 17, 2020
An Erg-driven transcriptional program controls B cell lymphopoiesisAshley P Ng, Hannah D Coughlan, Soroor Hediyeh-Zadeh, et al.
Molecular Cell|December 17, 2009
Recruitment of the linear ubiquitin chain assembly complex stabilizes the TNF-R1 signaling complex and is required for TNF-mediated gene inductionTobias L Haas, Christoph H Emmerich, Björn Gerlach, et al.
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