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CPT: Pharmacometrics & Systems Pharmacology|May 23, 2020
A Novel Physiologically Based Model of Creatinine Renal Disposition to Integrate Current Knowledge of Systems Parameters and Clinical ObservationsDaniel Scotcher, Vikram Arya, Xinning Yang, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|May 13, 2021
Hepatic Scaling Factors for In Vitro-In Vivo Extrapolation of Metabolic Drug Clearance in Patients with Colorectal Cancer with Liver MetastasisAreti-Maria Vasilogianni, Brahim Achour, Daniel Scotcher, et al.
Molecular Pharmaceutics|July 20, 2021
Physiologically Based Pharmacokinetic Modeling of Transporter-Mediated Hepatic Disposition of Imaging Biomarker Gadoxetate in RatsDaniel Scotcher, Nicola Melillo, Sirisha Tadimalla, et al.
Therapeutic Drug Monitoring|June 14, 2023
Using Prior Knowledge on Systems Through PBPK to Gain Further Insight into Routine Clinical Data on Trough Concentrations: The Case of Tacrolimus in Chronic Kidney DiseaseEman El-Khateeb, Rajkumar Chinnadurai, Jokha Al Qassabi, et al.
Molecular Pharmaceutics|April 24, 2026
Proteomics-Informed Physiologically Based Pharmacokinetic Modeling for Aldehyde Oxidase Substrates in Colorectal Cancer Liver MetastasisNihan Izat, Areti-Maria Vasilogianni, Zubida M Al-Majdoub, et al.
European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences|January 10, 2023
Toward systems-informed models for biologics disposition: covariates of the abundance of the neonatal Fc Receptor (FcRn) in human tissues and implications for pharmacokinetic modellingJill Barber, Zubida M Al-Majdoub, Narciso Couto, et al.
Clinical Pharmacokinetics|April 11, 2021
Clinical Investigation on Endogenous Biomarkers to Predict Strong OAT-Mediated Drug-Drug InteractionsMarie-Emilie Willemin, Thomas K Van Der Made, Ils Pijpers, et al.
Pharmaceutics|March 29, 2023
Use of In Vivo Imaging and Physiologically-Based Kinetic Modelling to Predict Hepatic Transporter Mediated Drug-Drug Interactions in RatsNicola Melillo, Daniel Scotcher, J Gerry Kenna, et al.
FEBS Letters|October 31, 2020
Mass spectrometry-based abundance atlas of ABC transporters in human liver, gut, kidney, brain and skinZubida M Al-Majdoub, Brahim Achour, Narciso Couto, et al.
Molecular Pharmaceutics|September 17, 2019
Quantitative Translation of Microfluidic Transporter <i>in Vitro</i> Data to <i>in Vivo</i> Reveals Impaired Albumin-Facilitated Indoxyl Sulfate Secretion in Chronic Kidney DiseaseThomas K van der Made, Michele Fedecostante, Daniel Scotcher, et al.
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