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Daniel T Gewirth

Showing results (21-30 of 35) with videos related to

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The Journal of Biological Chemistry|September 11, 2019
NECA derivatives exploit the paralog-specific properties of the site 3 side pocket of Grp94, the endoplasmic reticulum Hsp90John D Huck, Nanette L S Que, Robert M Immormino, et al.
Journal of Molecular Biology|April 14, 2009
Different poses for ligand and chaperone in inhibitor-bound Hsp90 and GRP94: implications for paralog-specific drug designRobert M Immormino, Louis E Metzger, Patrick N Reardon, et al.
The Journal of Biological Chemistry|November 10, 2018
Chaperome heterogeneity and its implications for cancer study and treatmentTai Wang, Anna Rodina, Mark P Dunphy, et al.
Journal of Medicinal Chemistry|March 13, 2018
Structure Based Design of a Grp94-Selective Inhibitor: Exploiting a Key Residue in Grp94 To Optimize Paralog-Selective BindingNanette L S Que, Vincent M Crowley, Adam S Duerfeldt, et al.
Plos One|November 9, 2016
Exploring the Functional Complementation between Grp94 and Hsp90Kevin A Maharaj, Nanette L S Que, Feng Hong, et al.
Journal of Medicinal Chemistry|January 6, 2006
Identification of potent water soluble purine-scaffold inhibitors of the heat shock protein 90Huazhong He, Danuta Zatorska, Joungnam Kim, et al.
Nature Chemical Biology|September 3, 2013
Paralog-selective Hsp90 inhibitors define tumor-specific regulation of HER2Pallav D Patel, Pengrong Yan, Paul M Seidler, et al.
Current Topics in Medicinal Chemistry|April 14, 2016
Clients and Oncogenic Roles of Molecular Chaperone gp96/grp94Ephraim A Ansa-Addo, Jessica Thaxton, Feng Hong, et al.
Proceedings of the National Academy of Sciences of the United States of America|March 14, 2024
Structural transitions modulate the chaperone activities of Grp94Yaa S Amankwah, Yasmeen Fleifil, Erin Unruh, et al.
Journal of Medicinal Chemistry|April 23, 2015
Structure-activity relationship in a purine-scaffold compound series with selectivity for the endoplasmic reticulum Hsp90 paralog Grp94Hardik J Patel, Pallav D Patel, Stefan O Ochiana, et al.
Pageof 4

Showing results (21-30 of 35) with videos related to

Sort By:
Pageof 4
The Journal of Biological Chemistry|September 11, 2019
NECA derivatives exploit the paralog-specific properties of the site 3 side pocket of Grp94, the endoplasmic reticulum Hsp90John D Huck, Nanette L S Que, Robert M Immormino, et al.
Journal of Molecular Biology|April 14, 2009
Different poses for ligand and chaperone in inhibitor-bound Hsp90 and GRP94: implications for paralog-specific drug designRobert M Immormino, Louis E Metzger, Patrick N Reardon, et al.
The Journal of Biological Chemistry|November 10, 2018
Chaperome heterogeneity and its implications for cancer study and treatmentTai Wang, Anna Rodina, Mark P Dunphy, et al.
Journal of Medicinal Chemistry|March 13, 2018
Structure Based Design of a Grp94-Selective Inhibitor: Exploiting a Key Residue in Grp94 To Optimize Paralog-Selective BindingNanette L S Que, Vincent M Crowley, Adam S Duerfeldt, et al.
Plos One|November 9, 2016
Exploring the Functional Complementation between Grp94 and Hsp90Kevin A Maharaj, Nanette L S Que, Feng Hong, et al.
Journal of Medicinal Chemistry|January 6, 2006
Identification of potent water soluble purine-scaffold inhibitors of the heat shock protein 90Huazhong He, Danuta Zatorska, Joungnam Kim, et al.
Nature Chemical Biology|September 3, 2013
Paralog-selective Hsp90 inhibitors define tumor-specific regulation of HER2Pallav D Patel, Pengrong Yan, Paul M Seidler, et al.
Current Topics in Medicinal Chemistry|April 14, 2016
Clients and Oncogenic Roles of Molecular Chaperone gp96/grp94Ephraim A Ansa-Addo, Jessica Thaxton, Feng Hong, et al.
Proceedings of the National Academy of Sciences of the United States of America|March 14, 2024
Structural transitions modulate the chaperone activities of Grp94Yaa S Amankwah, Yasmeen Fleifil, Erin Unruh, et al.
Journal of Medicinal Chemistry|April 23, 2015
Structure-activity relationship in a purine-scaffold compound series with selectivity for the endoplasmic reticulum Hsp90 paralog Grp94Hardik J Patel, Pallav D Patel, Stefan O Ochiana, et al.
Pageof 4