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Plos Biology|January 21, 2015
Structure-guided design of selective Epac1 and Epac2 agonistsFrank Schwede, Daniela Bertinetti, Carianne N Langerijs, et al.
ACS Chemical Biology|March 14, 2015
PKA-type I selective constrained peptide disruptors of AKAP complexesYuxiao Wang, Tienhuei G Ho, Eugen Franz, et al.
Molecular Endocrinology (Baltimore, Md.)|June 11, 2015
Rp-cAMPS Prodrugs Reveal the cAMP Dependence of First-Phase Glucose-Stimulated Insulin SecretionFrank Schwede, Oleg G Chepurny, Melanie Kaufholz, et al.
HGG Advances|May 20, 2026
Combined skeletal dysplasia and vasculopathy phenotypes associated with in-frame intragenic deletion in PRKACAK Nicole Weaver, Jan W Broeckel, Kari Brown, et al.
Proceedings of the National Academy of Sciences of the United States of America|May 7, 2026
A PKA-selective inhibitor captures an open but more ordered conformation of the PKA catalytic subunitJessica G H Bruystens, Jian Wu, Gerald Tan, et al.
Structure (London, England : 1993)|November 19, 2013
Structural basis for cyclic-nucleotide selectivity and cGMP-selective activation of PKG IGilbert Y Huang, Jeong Joo Kim, Albert S Reger, et al.
Nature Structural & Molecular Biology|October 6, 2022
A PKA inhibitor motif within SMOOTHENED controls Hedgehog signal transductionJohn T Happ, Corvin D Arveseth, Jessica Bruystens, et al.
Biorxiv : the Preprint Server for Biology|November 18, 2024
A Structural Mechanism for Noncanonical GPCR Signal Transduction in the Hedgehog PathwayWilliam P Steiner, Nathan Iverson, Varun Venkatakrishnan, et al.
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