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Translational Oncology|November 27, 2021
High-throughput ex vivo drug testing identifies potential drugs and drug combinations for NRAS-positive malignant melanomaLaura Kohtamäki, Mariliina Arjama, Siru Mäkelä, et al.
Blood Advances|January 4, 2018
Crosstalk between ROR1 and BCR pathways defines novel treatment strategies in mantle cell lymphomaHanna Karvonen, David Chiron, Wilhelmiina Niininen, et al.
Cell Death & Disease|February 26, 2026
ROR1-PI3K/AKT signaling drives adaptive resistance to cell cycle blockade in TP53 mutated ovarian cancerJuuli Raivola, Frida Rantanen, Alice Dini, et al.
The Journal of Biological Chemistry|September 12, 2015
Structural and Functional Characterization of the JH2 Pseudokinase Domain of JAK Family Tyrosine Kinase 2 (TYK2)Xiaoshan Min, Daniela Ungureanu, Sarah Maxwell, et al.
Nature Structural & Molecular Biology|August 16, 2011
The pseudokinase domain of JAK2 is a dual-specificity protein kinase that negatively regulates cytokine signalingDaniela Ungureanu, Jinhua Wu, Tuija Pekkala, et al.
Cell Death Discovery|July 3, 2023
ROR1-STAT3 signaling contributes to ovarian cancer intra-tumor heterogeneityEmilia Piki, Alice Dini, Juuli Raivola, et al.
Cell Death & Disease|September 29, 2020
Glucocorticoids induce differentiation and chemoresistance in ovarian cancer by promoting ROR1-mediated stemnessHanna Karvonen, Mariliina Arjama, Laura Kaleva, et al.
The Biochemical Journal|December 21, 2013
Mechanistic insights into activation and SOCS3-mediated inhibition of myeloproliferative neoplasm-associated JAK2 mutants from biochemical and structural analysesLeila N Varghese, Daniela Ungureanu, Nicholas P D Liau, et al.
Molecular Cell|July 4, 2020
Structural Insights into Pseudokinase Domains of Receptor Tyrosine KinasesJoshua B Sheetz, Sebastian Mathea, Hanna Karvonen, et al.
Cell Death & Disease|August 17, 2022
Multiomics characterization implicates PTK7 in ovarian cancer EMT and cell plasticity and offers strategies for therapeutic interventionJuuli Raivola, Alice Dini, Hanna Karvonen, et al.
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