Showing results (11-20 of 16) with videos related to
Sort By:
Pageof 2
You have reached the last page of results.This site can display upto 16 results.
Bioorganic & Medicinal Chemistry Letters|January 15, 2013
Discovery of a novel [3.2.1] benzo fused bicyclic sulfonamide-pyrazoles as potent, selective and efficacious γ-secretase inhibitorsXiaocong M Ye, Andrei W Konradi, Minghua Sun, et al.Bioorganic & Medicinal Chemistry Letters|August 8, 2009
Design, synthesis, and structure-activity relationship of novel orally efficacious pyrazole/sulfonamide based dihydroquinoline gamma-secretase inhibitorsAnh P Truong, Danielle L Aubele, Gary D Probst, et al.Bioorganic & Medicinal Chemistry Letters|March 26, 2013
Design and synthesis of highly selective, orally active Polo-like kinase-2 (Plk-2) inhibitorsSimeon Bowers, Anh P Truong, Michael Ye, et al.Chemmedchem|June 25, 2013
Selective and brain-permeable polo-like kinase-2 (Plk-2) inhibitors that reduce α-synuclein phosphorylation in rat brainDanielle L Aubele, Roy K Hom, Marc Adler, et al.Alzheimer'S Research & Therapy|December 31, 2010
Amyloid precursor protein selective gamma-secretase inhibitors for treatment of Alzheimer's diseaseGuriqbal S Basi, Susanna Hemphill, Elizabeth F Brigham, et al.Journal of Medicinal Chemistry|May 30, 2013
Discovery of (R)-4-cyclopropyl-7,8-difluoro-5-(4-(trifluoromethyl)phenylsulfonyl)-4,5-dihydro-1H-pyrazolo[4,3-c]quinoline (ELND006) and (R)-4-cyclopropyl-8-fluoro-5-(6-(trifluoromethyl)pyridin-3-ylsulfonyl)-4,5-dihydro-2H-pyrazolo[4,3-c]quinoline (ELND007): metabolically stable γ-secretase Inhibitors that selectively inhibit the production of amyloid-β over NotchGary Probst, Danielle L Aubele, Simeon Bowers, et al.Pageof 2