Showing results (21-30 of 31) with videos related to
Sort By:
Pageof 4
Cancer Research|July 3, 2025
RIT1M90I Is a Driver of Lung Adenocarcinoma Tumorigenesis and Resistance to Targeted TherapyAshley V DiMarco, Mirunalini Ravichandran, Jeff Lau, et al.Cancer Research Communications|July 31, 2023
Identification of an Imidazopyridine-based Compound as an Oral Selective Estrogen Receptor Degrader for Breast Cancer TherapyMengwu Pan, Valeria Solozobova, Nane C Kuznik, et al.Cell Chemical Biology|May 16, 2025
Engineering ERα degraders with pleiotropic ubiquitin ligase ligands maximizes therapeutic efficacy by co-opting distinct effector ligasesAnna Shemorry, Willem den Besten, Melinda M Mulvihill, et al.Biorxiv : the Preprint Server for Biology|July 18, 2023
SALL4B, not targeted by IMiD, is important for SALL4-mediated tumorigenesisKim Anh L Vu, Kalpana Kumari, Bee Hui Liu, et al.Cancer Discovery|August 4, 2021
Rlf-Mycl Gene Fusion Drives Tumorigenesis and Metastasis in a Mouse Model of Small Cell Lung CancerMetamia Ciampricotti, Triantafyllia Karakousi, Allison L Richards, et al.Nature Communications|December 9, 2025
Fragment-based discovery enables direct targeting of the melanoma oncogene MITFDeborah Castelletti, Jürgen Hinrichs, Goran Malojčić, et al.Nature|May 7, 2025
Targeting the SHOC2-RAS interaction in RAS-mutant cancersZachary J Hauseman, Frédéric Stauffer, Kim S Beyer, et al.Journal of Medicinal Chemistry|September 29, 2023
Identification of GDC-1971 (RLY-1971), a SHP2 Inhibitor Designed for the Treatment of Solid TumorsAlexander M Taylor, Bret R Williams, Fabrizio Giordanetto, et al.Nature Cancer|June 5, 2023
An allosteric pan-TEAD inhibitor blocks oncogenic YAP/TAZ signaling and overcomes KRAS G12C inhibitor resistanceThijs J Hagenbeek, Jason R Zbieg, Marc Hafner, et al.Clinical Cancer Research : an Official Journal of the American Association for Cancer Research|October 27, 2025
PI3Kα Inhibitor and Degrader Inavolisib Can Co-opt FGFR2 to Enhance Responses in Patients with PIK3CA-Mutated Solid Tumors and in Preclinical ModelsDejan Juric, Kyung Song, Radia M Johnson, et al.Pageof 4