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Molecular Cancer Therapeutics|October 20, 2021
Overcoming Gemcitabine Resistance in Pancreatic Cancer Using the BCL-XL-Specific Degrader DT2216Dinesh Thummuri, Sajid Khan, Patrick W Underwood, et al.
Haematologica|April 20, 2023
Co-targeting BCL-XL and BCL-2 by PROTAC 753B eliminates leukemia cells and enhances efficacy of chemotherapy by targeting senescent cellsYannan Jia, Lina Han, Cassandra L Ramage, et al.
Cell|April 18, 2025
CD36-mediated endocytosis of proteolysis-targeting chimerasZhengyu Wang, Bo-Syong Pan, Rajesh Kumar Manne, et al.
Nature|June 21, 2023
Structural insights into BCDX2 complex function in homologous recombinationYashpal Rawal, Lijia Jia, Aviv Meir, et al.
JCI Insight|September 8, 2022
Targeting BCL-XL in fibrolamellar hepatocellular carcinomaBassem Shebl, Denise Ng, Gadi Lalazar, et al.
Nucleic Acids Research|November 12, 2023
TATDN2 resolution of R-loops is required for survival of BRCA1-mutant cancer cellsAruna S Jaiswal, Arijit Dutta, Gayathri Srinivasan, et al.
Molecular Cancer Therapeutics|June 26, 2025
Targeting DDR2 for Treating Pancreatic CancerChris Tp Do, Prabhakar Pitta Venkata, Jack Y Prochnau, et al.
Oncogene|February 12, 2020
Cancer cell-intrinsic function of CD177 in attenuating β-catenin signalingPaige N Kluz, Ryan Kolb, Qing Xie, et al.
Nature Communications|April 26, 2020
Using proteolysis-targeting chimera technology to reduce navitoclax platelet toxicity and improve its senolytic activityYonghan He, Xuan Zhang, Jianhui Chang, et al.
Blood|April 10, 2024
NSD2 drives t(4;14) myeloma cell dependence on adenylate kinase 2 by diverting one-carbon metabolism to the epigenomeAmin Sobh, Elena Encinas, Alisha Patel, et al.
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