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Biorxiv : the Preprint Server for Biology|March 22, 2023
Dynamic network-guided CRISPRi screen reveals CTCF loop-constrained nonlinear enhancer-gene regulatory activity in cell state transitionsRenhe Luo, Jielin Yan, Jin Woo Oh, et al.Nature Genetics|July 24, 2023
Dynamic network-guided CRISPRi screen identifies CTCF-loop-constrained nonlinear enhancer gene regulatory activity during cell state transitionsRenhe Luo, Jielin Yan, Jin Woo Oh, et al.Biorxiv : the Preprint Server for Biology|January 9, 2026
A stem cell knockout village reveals lineage rewiring and a non-canonical islet cell fate in monogenic diabetesDingyu Liu, Bicna Song, Zhaoheng Li, et al.Biorxiv : the Preprint Server for Biology|November 14, 2023
Decoding Heterogenous Single-cell Perturbation ResponsesBicna Song, Dingyu Liu, Weiwei Dai, et al.Nature Genetics|May 22, 2019
Genome-scale screens identify JNK-JUN signaling as a barrier for pluripotency exit and endoderm differentiationQing V Li, Gary Dixon, Nipun Verma, et al.Nature Cell Biology|February 26, 2025
Decoding heterogeneous single-cell perturbation responsesBicna Song, Dingyu Liu, Weiwei Dai, et al.Biorxiv : the Preprint Server for Biology|April 10, 2026
A Genetically Engineered Human Organoid Model Reveals Distinct Genetic and Epigenetic Barriers of Lineage Plasticity in Early PDAC TransformationXian Zhang, Wilfred Wong, Hyein S Cho, et al.Nature Cell Biology|July 5, 2022
CRISPR screening uncovers a central requirement for HHEX in pancreatic lineage commitment and plasticity restrictionDapeng Yang, Hyunwoo Cho, Zakieh Tayyebi, et al.Developmental Cell|May 20, 2026
Human pancreatic progenitor organoids define genetic and epigenetic barriers to early PDAC transformationXian Zhang, Wilfred Wong, Hyein S Cho, et al.Pageof 12