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Journal of Neurochemistry|November 15, 2006
Expression and localization of Parkinson's disease-associated leucine-rich repeat kinase 2 in the mouse brainShinji Higashi, Darren J Moore, Rebecca E Colebrooke, et al.
Neurobiology of Disease|August 26, 2024
Heterozygous loss of Engrailed-1 and α-synucleinopathy (En1/SYN): A dual-hit preclinical mouse model of Parkinson's disease, analyzed with artificial intelligenceLucas Stetzik, Gabriela Mercado, Jennifer A Steiner, et al.
Human Molecular Genetics|December 22, 2011
PARK9-associated ATP13A2 localizes to intracellular acidic vesicles and regulates cation homeostasis and neuronal integrityDavid Ramonet, Agata Podhajska, Klodjan Stafa, et al.
BMC Neuroscience|November 30, 2007
Dynamic and redundant regulation of LRRK2 and LRRK1 expressionSaskia Biskup, Darren J Moore, Alexis Rea, et al.
Proceedings of the National Academy of Sciences of the United States of America|July 8, 2020
Dopaminergic neurodegeneration induced by Parkinson's disease-linked G2019S LRRK2 is dependent on kinase and GTPase activityAn Phu Tran Nguyen, Elpida Tsika, Kaela Kelly, et al.
Proceedings of the National Academy of Sciences of the United States of America|November 5, 2005
Parkinson's disease-associated mutations in leucine-rich repeat kinase 2 augment kinase activityAndrew B West, Darren J Moore, Saskia Biskup, et al.
Brain Communications|October 27, 2021
Neuronal VPS35 deletion induces spinal cord motor neuron degeneration and early post-natal lethalityDorian Sargent, Lindsey A Cunningham, Dylan J Dues, et al.
Translational Neurodegeneration|June 19, 2025
Pathological α-synuclein elicits granulovacuolar degeneration independent of tauDylan J Dues, Madalynn L Erb, Alysa Kasen, et al.
Plos Genetics|April 14, 2010
GTPase activity plays a key role in the pathobiology of LRRK2Yulan Xiong, Candice E Coombes, Austin Kilaru, et al.
Proceedings of the National Academy of Sciences of the United States of America|December 15, 2005
Leucine-rich repeat kinase 2 (LRRK2) interacts with parkin, and mutant LRRK2 induces neuronal degenerationWanli W Smith, Zhong Pei, Haibing Jiang, et al.
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