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Journal of Medical Case Reports|October 12, 2011
Methadone adverse reaction presenting with large increase in plasma methadone binding: a case seriesWenjie J Lu, Weidong Zhou, Yvonne Kreutz, et al.Journal of Breath Research|December 22, 2012
Is (+)-[13C]-pantoprazole better than (±)-[13C]-pantoprazole for the breath test to evaluate CYP2C19 enzyme activity?David L Thacker, Anil Modak, David A Flockhart, et al.Clinical Pharmacokinetics|September 12, 2002
Clinical significance of the cytochrome P450 2C19 genetic polymorphismZeruesenay Desta, Xiaojiong Zhao, Jae-Gook Shin, et al.Cancer Chemotherapy and Pharmacology|February 10, 2009
Inhibition of drug metabolizing cytochrome P450s by the aromatase inhibitor drug letrozole and its major oxidative metabolite 4,4'-methanol-bisbenzonitrile in vitroSeongwook Jeong, Margaret M Woo, David A Flockhart, et al.The Journal of Pharmacology and Experimental Therapeutics|May 26, 2004
Comprehensive evaluation of tamoxifen sequential biotransformation by the human cytochrome P450 system in vitro: prominent roles for CYP3A and CYP2D6Zeruesenay Desta, Bryan A Ward, Nadia V Soukhova, et al.Cancer Chemotherapy and Pharmacology|February 3, 2005
Endoxifen (4-hydroxy-N-desmethyl-tamoxifen) has anti-estrogenic effects in breast cancer cells with potency similar to 4-hydroxy-tamoxifenYoung Chai Lim, Zeruesenay Desta, David A Flockhart, et al.The Oncologist|February 16, 2006
Interethnic differences in genetic polymorphisms of CYP2D6 in the U.S. population: clinical implicationsStephen Bernard, Kathleen A Neville, Anne T Nguyen, et al.Drug Metabolism and Disposition: the Biological Fate of Chemicals|April 16, 2002
Triethylenethiophosphoramide is a specific inhibitor of cytochrome P450 2B6: implications for cyclophosphamide metabolismJames M Rae, Nadia V Soukhova, David A Flockhart, et al.Journal of Medicinal Chemistry|June 5, 2013
Synthesis of mixed (E,Z)-, (E)-, and (Z)-norendoxifen with dual aromatase inhibitory and estrogen receptor modulatory activitiesWei Lv, Jinzhong Liu, Deshun Lu, et al.The Journal of Pharmacology and Experimental Therapeutics|October 29, 2004
The effects of tamoxifen and its metabolites on platelet function and release of reactive oxygen intermediatesOlga Vitseva, David A Flockhart, Yan Jin, et al.Pageof 14