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Plos One|July 18, 2022
Treatment with a VEGFR-2 antibody results in intra-tumor immune modulation and enhances anti-tumor efficacy of PD-L1 blockade in syngeneic murine tumor modelsYanxia Li, Nelusha Amaladas, Marguerita O'Mahony, et al.Journal for Immunotherapy of Cancer|June 6, 2018
Targeting the TGFβ pathway with galunisertib, a TGFβRI small molecule inhibitor, promotes anti-tumor immunity leading to durable, complete responses, as monotherapy and in combination with checkpoint blockadeRikke B Holmgaard, David A Schaer, Yanxia Li, et al.Cell Reports|March 15, 2018
The CDK4/6 Inhibitor Abemaciclib Induces a T Cell Inflamed Tumor Microenvironment and Enhances the Efficacy of PD-L1 Checkpoint BlockadeDavid A Schaer, Richard P Beckmann, Jack A Dempsey, et al.Clinical Cancer Research : an Official Journal of the American Association for Cancer Research|August 15, 2019
The Folate Pathway Inhibitor Pemetrexed Pleiotropically Enhances Effects of Cancer ImmunotherapyDavid A Schaer, Sandaruwan Geeganage, Nelusha Amaladas, et al.Pageof 2