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Journal of Medicinal Chemistry|December 30, 2020
Development of Orally Efficacious Allosteric Inhibitors of TNFα via Fragment-Based Drug DesignJustin D Dietrich, Kenton L Longenecker, Noel S Wilson, et al.Bioorganic & Medicinal Chemistry Letters|December 25, 2010
Discovery of novel hepatoselective HMG-CoA reductase inhibitors for treating hypercholesterolemia: a bench-to-bedside case study on tissue selective drug distributionJeffrey A Pfefferkorn, John Litchfield, Richard Hutchings, et al.Journal of Medicinal Chemistry|December 27, 2011
Discovery of (S)-6-(3-cyclopentyl-2-(4-(trifluoromethyl)-1H-imidazol-1-yl)propanamido)nicotinic acid as a hepatoselective glucokinase activator clinical candidate for treating type 2 diabetes mellitusJeffrey A Pfefferkorn, Angel Guzman-Perez, John Litchfield, et al.Journal of Medicinal Chemistry|April 4, 2024
Discovery of Small Molecule Interleukin 17A Inhibitors with Novel Binding Mode and Stoichiometry: Optimization of DNA-Encoded Chemical Library Hits to In Vivo Active CompoundsAshley L Ramos, Eric R Goedken, Kristine E Frank, et al.Pageof 3