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The Journal of Clinical Investigation|September 8, 2022
The druggable transcription factor Fli-1 regulates T cell immunity and tolerance in graft-versus-host diseaseSteven D Schutt, Yongxia Wu, Arjun Kharel, et al.
Blood Advances|January 24, 2022
MicroRNA-31 regulates T-cell metabolism via HIF1α and promotes chronic GVHD pathogenesis in miceYongxia Wu, Corey Mealer, Steven Schutt, et al.
The Journal of Clinical Investigation|May 3, 2019
Thioredoxin-1 confines T cell alloresponse and pathogenicity in graft-versus-host diseaseM Hanief Sofi, Yongxia Wu, Steven D Schutt, et al.
JCI Insight|May 19, 2017
Ceramide synthesis regulates T cell activity and GVHD developmentM Hanief Sofi, Jessica Heinrichs, Mohammed Dany, et al.
Cellular & Molecular Immunology|January 27, 2021
STING negatively regulates allogeneic T-cell responses by constraining antigen-presenting cell functionYongxia Wu, Chih-Hang Anthony Tang, Corey Mealer, et al.
Blood Advances|February 28, 2018
Inhibition of the IRE-1α/XBP-1 pathway prevents chronic GVHD and preserves the GVL effect in miceSteven D Schutt, Yongxia Wu, Chih-Hang Anthony Tang, et al.
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research|January 11, 2020
Targeting the Complement Alternative Pathway Permits Graft Versus Leukemia Activity while Preventing Graft Versus Host DiseaseHung Nguyen, Ali Alawieh, David Bastian, et al.
JCI Insight|December 21, 2018
Complement C3a and C5a receptors promote GVHD by suppressing mitophagy in recipient dendritic cellsHung Nguyen, Sandeepkumar Kuril, David Bastian, et al.
Leukemia|May 5, 2022
Ceramide synthase 6 impacts T-cell allogeneic response and graft-versus-host disease through regulating N-RAS/ERK pathwayM Hanief Sofi, Linlu Tian, Steven Schutt, et al.
Proceedings of the National Academy of Sciences of the United States of America|February 1, 2018
Targeting JAK2 reduces GVHD and xenograft rejection through regulation of T cell differentiationBrian C Betts, David Bastian, Supinya Iamsawat, et al.
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