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Journal of Chemical Information and Modeling
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December 17, 2013
Comparative study on the use of docking and Bayesian categorization to predict ligand binding to nicotinic acetylcholine receptors (nAChRs) subtypes
David C Kombo, Merouane Bencherif
Journal of Medicinal Chemistry
|
May 26, 2025
The Logic of Chemical Optimization
David C Kombo, Matthew J LaMarche
Proteins
|
May 29, 2024
Application of artificial intelligence and machine learning techniques to the analysis of dynamic protein sequences
David C Kombo, Matthew J LaMarche, Chilaluck C Konkankit, et al.
Bioorganic & Medicinal Chemistry Letters
|
August 14, 2013
Computational studies of novel carbonyl-containing diazabicyclic ligands interacting with α4β2 nicotinic acetylcholine receptor (nAChR) reveal alternative binding modes
David C Kombo, Anatoly A Mazurov, Jon-Paul Strachan, et al.
Bioorganic & Medicinal Chemistry Letters
|
July 27, 2013
QM-polarized ligand docking accurately predicts the trend in binding affinity of a series of arylmethylene quinuclidine-like derivatives at the α4β2 and α3β4 nicotinic acetylcholine receptors (nAChRs)
David C Kombo, Vladimir P Grinevich, Terry A Hauser, et al.
Journal of Chemical Information and Modeling
|
December 19, 2012
3D molecular descriptors important for clinical success
David C Kombo, Kartik Tallapragada, Rachit Jain, et al.
Bioorganic & Medicinal Chemistry Letters
|
May 23, 2013
Novel nicotinic acetylcholine receptor agonists containing carbonyl moiety as a hydrogen bond acceptor
Anatoly A Mazurov, David C Kombo, Srinivasa Akireddy, et al.
ACS Omega
|
July 8, 2024
Predictions of Colloidal Molecular Aggregation Using AI/ML Models
David C Kombo, J David Stepp, Sungtaek Lim, et al.
Bioorganic & Medicinal Chemistry Letters
|
December 20, 2011
Discovery of novel α7 nicotinic acetylcholine receptor ligands via pharmacophoric and docking studies of benzylidene anabaseine analogs
David C Kombo, Anatoly A Mazurov, Joseph Chewning, et al.
European Journal of Medicinal Chemistry
|
August 23, 2014
Identification and pharmacological characterization of 3,6-diazabicyclo[3.1.1]heptane-3-carboxamides as novel ligands for the α4β2 and α6/α3β2β3 nicotinic acetylcholine receptors (nAChRs)
Jon-Paul Strachan, David C Kombo, Anatoly Mazurov, et al.
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Search research articles
Search
Showing results (1-10 of 14) with videos related to
Sort By:
Page
of 2
Journal of Chemical Information and Modeling
|
December 17, 2013
Comparative study on the use of docking and Bayesian categorization to predict ligand binding to nicotinic acetylcholine receptors (nAChRs) subtypes
David C Kombo, Merouane Bencherif
Journal of Medicinal Chemistry
|
May 26, 2025
The Logic of Chemical Optimization
David C Kombo, Matthew J LaMarche
Proteins
|
May 29, 2024
Application of artificial intelligence and machine learning techniques to the analysis of dynamic protein sequences
David C Kombo, Matthew J LaMarche, Chilaluck C Konkankit, et al.
Bioorganic & Medicinal Chemistry Letters
|
August 14, 2013
Computational studies of novel carbonyl-containing diazabicyclic ligands interacting with α4β2 nicotinic acetylcholine receptor (nAChR) reveal alternative binding modes
David C Kombo, Anatoly A Mazurov, Jon-Paul Strachan, et al.
Bioorganic & Medicinal Chemistry Letters
|
July 27, 2013
QM-polarized ligand docking accurately predicts the trend in binding affinity of a series of arylmethylene quinuclidine-like derivatives at the α4β2 and α3β4 nicotinic acetylcholine receptors (nAChRs)
David C Kombo, Vladimir P Grinevich, Terry A Hauser, et al.
Journal of Chemical Information and Modeling
|
December 19, 2012
3D molecular descriptors important for clinical success
David C Kombo, Kartik Tallapragada, Rachit Jain, et al.
Bioorganic & Medicinal Chemistry Letters
|
May 23, 2013
Novel nicotinic acetylcholine receptor agonists containing carbonyl moiety as a hydrogen bond acceptor
Anatoly A Mazurov, David C Kombo, Srinivasa Akireddy, et al.
ACS Omega
|
July 8, 2024
Predictions of Colloidal Molecular Aggregation Using AI/ML Models
David C Kombo, J David Stepp, Sungtaek Lim, et al.
Bioorganic & Medicinal Chemistry Letters
|
December 20, 2011
Discovery of novel α7 nicotinic acetylcholine receptor ligands via pharmacophoric and docking studies of benzylidene anabaseine analogs
David C Kombo, Anatoly A Mazurov, Joseph Chewning, et al.
European Journal of Medicinal Chemistry
|
August 23, 2014
Identification and pharmacological characterization of 3,6-diazabicyclo[3.1.1]heptane-3-carboxamides as novel ligands for the α4β2 and α6/α3β2β3 nicotinic acetylcholine receptors (nAChRs)
Jon-Paul Strachan, David C Kombo, Anatoly Mazurov, et al.
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